An objective comparison of detection and segmentation algorithms for artefacts in clinical endoscopy

被引:52
|
作者
Ali, Sharib [1 ]
Zhou, Felix [2 ]
Braden, Barbara [4 ]
Bailey, Adam [4 ]
Yang, Suhui [6 ]
Cheng, Guanju [6 ]
Zhang, Pengyi [7 ]
Li, Xiaoqiong [7 ]
Kayser, Maxime [8 ]
Soberanis-Mukul, Roger D. [8 ]
Albarqouni, Shadi [8 ]
Wang, Xiaokang [9 ]
Wang, Chunqing [15 ]
Watanabe, Seiryo [10 ]
Oksuz, Ilkay [11 ,20 ]
Ning, Qingtian [17 ]
Yang, Shufan [16 ]
Khan, Mohammad Azam [18 ]
Gao, Xiaohong W. [19 ]
Realdon, Stefano [3 ,5 ]
Loshchenov, Maxim [13 ]
Schnabel, Julia A. [11 ]
East, James E. [4 ]
Wagnieres, Georges [12 ]
Loschenov, Victor B. [13 ]
Grisan, Enrico [14 ,21 ]
Daul, Christian [3 ]
Blondel, Walter [3 ]
Rittscher, Jens [1 ]
机构
[1] Univ Oxford, Inst Biomed Engn, Big Data Inst, Dept Engn Sci, Oxford, England
[2] Univ Oxford, Ludwig Inst Canc Res, Oxford, England
[3] Univ Lorraine, CNRS, UMR 7039, CRAN, Nancy, France
[4] Univ Oxford, Nuffield Dept Med, Expt Med Div, Translat Gastroenterol Unit,John Radcliffe Hosp, Oxford, England
[5] IOV IRCCS, Inst Onclol Veneto, Padua, Italy
[6] Ping An Technol Shenzhen Co Ltd, Shenzhen, Peoples R China
[7] Beijing Inst Technol, Beijing, Peoples R China
[8] Tech Univ Munich, Munich, Germany
[9] Univ Calif Davis, Dept Biomed Engn, Davis, CA 95616 USA
[10] Osaka Univ, Dept Bioinformat Engn, Suita, Osaka, Japan
[11] Kings Coll London, Sch Biomed Engn & Imaging Sci, London, England
[12] Swiss Fed Inst Technol Lausanne EPFL, Lausanne, Switzerland
[13] Russian Acad Sci, AM Prokhorov Gen Phys Inst, Moscow, Russia
[14] Univ Padua, Dept Informat Engn, Padua, Italy
[15] Tiantan Hosp, Dept Ultrasound Imaging, Beijing, Peoples R China
[16] Univ Glasgow, Sch Engn, Glasgow, Lanark, Scotland
[17] Shanghai Jiao Tong Univ, Dept Automat, Shanghai, Peoples R China
[18] Korea Univ, Dept Comp Sci & Engn, Seoul, South Korea
[19] Middlesex Univ, Dept Comp Sci, London, England
[20] Istanbul Tech Univ, Dept Comp Engn, Istanbul, Turkey
[21] London South Bank Univ, Sch Engn, London, England
基金
英国工程与自然科学研究理事会;
关键词
D O I
10.1038/s41598-020-59413-5
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
We present a comprehensive analysis of the submissions to the first edition of the Endoscopy Artefact Detection challenge (EAD). Using crowd-sourcing, this initiative is a step towards understanding the limitations of existing state-of-the-art computer vision methods applied to endoscopy and promoting the development of new approaches suitable for clinical translation. Endoscopy is a routine imaging technique for the detection, diagnosis and treatment of diseases in hollow-organs; the esophagus, stomach, colon, uterus and the bladder. However the nature of these organs prevent imaged tissues to be free of imaging artefacts such as bubbles, pixel saturation, organ specularity and debris, all of which pose substantial challenges for any quantitative analysis. Consequently, the potential for improved clinical outcomes through quantitative assessment of abnormal mucosal surface observed in endoscopy videos is presently not realized accurately. The EAD challenge promotes awareness of and addresses this key bottleneck problem by investigating methods that can accurately classify, localize and segment artefacts in endoscopy frames as critical prerequisite tasks. Using a diverse curated multi-institutional, multi-modality, multi-organ dataset of video frames, the accuracy and performance of 23 algorithms were objectively ranked for artefact detection and segmentation. The ability of methods to generalize to unseen datasets was also evaluated. The best performing methods (top 15%) propose deep learning strategies to reconcile variabilities in artefact appearance with respect to size, modality, occurrence and organ type. However, no single method outperformed across all tasks. Detailed analyses reveal the shortcomings of current training strategies and highlight the need for developing new optimal metrics to accurately quantify the clinical applicability of methods.
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页数:15
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