The prevalence of anemia and iron deficiency in IBD outpatients in Scandinavia

被引:79
|
作者
Bager, Palle [1 ]
Befrits, Ragnar [2 ]
Wikman, Ola [3 ]
Lindgren, Stefan [4 ]
Moum, Bjorn [5 ]
Hjortswang, Henrik [6 ]
Dahlerup, Jens F. [1 ]
机构
[1] Aarhus Univ Hosp, Dept Med Hepatol & Gastroenterol 5, Aarhus, Denmark
[2] Karolinska Univ Hosp, Dept Gastroenterol & Hepatol, Stockholm, Sweden
[3] Stockholm S Gen Hosp, Dept Med, Stockholm, Sweden
[4] Lund Univ, Dept Clin Sci, Div Gastroenterol Hepatol, Malmo Univ Hosp, S-22100 Lund, Sweden
[5] Oslo Univ Hosp, Dept Gastroenterol, Oslo, Norway
[6] Linkoping Univ Hosp, Dept Endocrinol & Gastroenterol, Linkoping, Sweden
关键词
Anemia; iron deficiency; inflammatory bowel diseases; outpatients; INFLAMMATORY-BOWEL-DISEASE; QUALITY-OF-LIFE; SUCROSE;
D O I
10.3109/00365521.2010.533382
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Objective. To evaluate the prevalence of anemia and iron deficiency (ID) among patients with inflammatory bowel disease (IBD) in the Scandinavian countries. Material and methods. A cross-sectional study including 429 IBD patients from six centers in Denmark, Norway and Sweden. Patients were screened for anemia and ID. Each center included similar to 5% of their IBD cohort. Patients were consecutively seen in the outpatient clinic, regardless of disease activity and whether the visits were scheduled or not. Results. The overall prevalence of anemia was 19% (95% CI: 16--23%). The prevalence was higher among patients with Crohn's disease than among patients with ulcerative colitis (p = 0.01). The etiology of anemia was as follows: iron deficiency anemia (20%), anemia of chronic disease (12%), and both conditions (68%). Less than 5% had folate acid or vitamin B12 deficiency. ID was found in 35% (CI: 31-40%) of the patients. Conclusions. Anemia was present in every fifth IBD patient and ID in every third IBD patient.
引用
收藏
页码:304 / 309
页数:6
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