Hyperthermia for locally advanced breast cancer

被引：44

作者：

Zagar, Timothy M. ^{[1
]}

Oleson, James R. ^{[1
]}

Vujaskovic, Zeljko ^{[1
]}

Dewhirst, Mark W. ^{[1
]}

Craciunescu, Oana I. ^{[1
]}

Blackwell, Kimberly L. ^{[2
]}

Prosnitz, Leonard R. ^{[1
]}

Jones, Ellen L. ^{[3
]}

机构：

[1] Duke Univ, Med Ctr, Dept Radiat Oncol, Durham, NC 27710 USA

[2] Duke Univ, Med Ctr, Dept Med, Div Med Oncol, Durham, NC 27710 USA

[3] Univ N Carolina, Dept Radiat Oncol, Canc Hosp, Chapel Hill, NC USA

来源：

INTERNATIONAL JOURNAL OF HYPERTHERMIA | 2010年 / 26卷 / 07期

基金：

美国国家卫生研究院;

关键词：

hyperthermia; locally advanced breast cancer; radiation; SURGICAL ADJUVANT BREAST; CONCURRENT RADIATION-THERAPY; PROJECT PROTOCOL B-27; NEOADJUVANT CHEMOTHERAPY; PHASE-I/II; PREOPERATIVE CHEMOTHERAPY; CHEST-WALL; IN-VITRO; CARCINOMA; PACLITAXEL;

D O I：

10.3109/02656736.2010.501051

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hyperthermia (HT) has a proven benefit for treating superficial malignancies, particularly chest wall recurrences of breast cancer. There has been less research utilising HT in patients with locally advanced breast cancer (LABC), but available data are promising. HT has been combined with chemotherapy and/or radiotherapy in the neoadjuvant, definitive and adjuvant setting, albeit in series with small numbers of patients. There is only one phase III trial that examines hyperthermia in LABC, also with relatively small numbers of patients. The goal of this review is to highlight important research utilising HT in patients with LABC as well as to suggest future directions for its use.

引用

页码：618 / 624

页数：7

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