Inhaled salbutamol decreases blood ammonia levels during exercise in normal subjects

被引：7
|
作者：
Matthys, D
Calders, P
Pannier, JL
机构：
[1] Ghent Univ Hosp, Dept Pediat, B-9000 Ghent, Belgium
[2] Univ Ghent, Lab Normal & Pathol Physiol, B-9000 Ghent, Belgium
[3] Univ Ghent, Inst Phys Educ, B-9000 Ghent, Belgium
来源：
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY | 1998年 / 79卷 / 01期
关键词：
exercise; ammonia; beta-adrenoreceptors; salbutamol;
D O I：
10.1007/s004210050482
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
The present study examines the effect of salbutamol, a beta 2-adrenoreceptor agonist, on blood ammonia levels during an incremental cycle exercise test in healthy non-asthmatic subjects. Blood ammonia levels were lower after inhalation of 400 meg of salbutamol than after placebo during submaximal exercise: 33 +/- 2 mu mol.l(-1) vs 48 +/- 9 mu mol.l(-1) at 220 W and 39 +/- 2 mu mol.l(-1) vs 50 +/- 4 mu mol.l(-1) at 260 W. At peak exercise there were no significant differences. The results suggest that beta 2-adrenoreceptors are involved in the regulation of blood ammonia during exercise.
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页码：110 / 113
页数：4
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