Antigen-induced changes in odor attractiveness and reproductive output in male mice

被引：8
|
作者：
Gerlinskaya, Ludmila A. [2 ]
Shnayder, Elena P. [1 ]
Dotsenko, Anna S. [1 ]
Maslennikova, Svetlana O. [1 ]
Zavjalov, Eugene L. [1 ]
Moshkin, Mikhail P. [1 ,3 ]
机构：
[1] RAS, Siberian Branch, Dept Ecol Mammalian Genet, Inst Cytol & Genet, Novosibirsk 630090, Russia
[2] RAS, Siberian Branch, Inst Systemat & Ecol Anim, Novosibirsk 630091, Russia
[3] Tomsk State Univ, Dept Zool & Anim Ecol, Tomsk 634050, Russia
来源：
BRAIN BEHAVIOR AND IMMUNITY | 2012年 / 26卷 / 03期
关键词：
Antigenic stimulation; Female choice; Hemocyanin; Immunoresponsiveness; Odor preference; Reproductive output; PARASITIZED MALE-MICE; TERMINAL INVESTMENT; FEMALE MICE; IMMUNE CHALLENGE; ACTIVATION; BEHAVIOR; RESPONSES; IMMUNOCOMPETENCE; CHEMOSIGNALS; MECHANISMS;
D O I：
10.1016/j.bbi.2011.11.010
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Modulation of social signals by antigen-induced immunoenhancement is a significant component of behavioral and reproductive adaptations of a host population to parasitic pressure. To investigate this concept, we studied odor attractiveness and reproductive output of ICR male mice treated with keyhole limpet hemocyanin (KLH) as an antigenic stimulus. We collected urine samples for olfactory preference tests (control vs. KLH administration) on different days following treatment. We found that the differences in odor attractiveness between control and immunized males, which were observed on the 3rd day, disappeared soon afterwards. Odor attractiveness of male mice positively correlated with their immunoresponsiveness, which was assessed by the sum of anti-KLH IgG1 and anti-KLH IgG2a titers. According to the hypothesis of terminal investment, antigen-treated males had higher reproductive output in comparison with control males and produced more progeny as a result. (C) 2011 Elsevier Inc. All rights reserved.
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页码：451 / 458
页数：8
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