Responses of residual and recommended nitrogen (N), phosphorus (P), potassium (K), sulfur (S) nutrient amounts and crops (yield, emergence, and height) to 0, 60, 100, and 140% soil test-based fertilizer rate applications on the same plots for six years under minimum tillage and direct seeding systems were assessed. Higher fertilizer rates increased residual nitrate (NO3)-N, extractable K, and sulfate (SO4)-S amounts after a low crop yield year, particularly NO3-N, without temporal trend. Increase in residual available P level at higher fertilizer rates showed a positive temporal trend. Lower N, P, and S fertilizer rates were recommended to crops after higher residual NO3-N, available P, and SO4-S levels. Crops effectively used the residual nutrients. Compared to 0%, the relative seed yields at 60, 100, and 140% rates increased with years of fertilization. There were no clear responses of measured soil and crop parameters to seeding systems. Testing residual nutrients can optimize fertilizer use and crop yields.