Metal-free synthesis of 2-mercaptobenzothiazoles and 6-(4-substituted-1H-1,2,3-triazol-1-yl)-2-mercaptobenzothiazoles via microwave-assisted synthesis pathway

被引：2
|
作者：
Tung, Truong Thanh [1 ,2 ]
Huy, Luong Xuan [1 ,2 ]
机构：
[1] PHENIKAA Univ, Fac Pharm, Hanoi 12116, Vietnam
[2] PHENIKAA Univ, PHENIKAA Inst Adv Study PIAS, Hanoi, Vietnam
来源：
SYNTHETIC COMMUNICATIONS | 2020年 / 50卷 / 13期
关键词：
microwave-assisted synthesis; metal-free; 2-mercaptobenzothiazole; DERIVATIVES; BENZOTHIAZOLE; 2-MERCAPTO; DESIGN;
D O I：
10.1080/00397911.2020.1761984
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple, efficient, and metal-free methodology for the preparation of 2-mercaptobenzothiazole and derivatives in excellent yields via microwave-assisted pathway is reported. Our condition provides a convenient protocol for the synthesis of a diverse collection of 2-mercaptobenzothiazoles and 6-(4-substituted-1H-1,2,3-triazol-1-yl)-2-mercaptobenzothiazoles with a very simple purification process. This report provides an alternative protocol for fast access to the wide range of compounds for sequence synthesis and biological studies.
引用
收藏
页码：2007 / 2014
页数：8
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