Erythema Nodosum-Like Panniculitis as a False-Positive 18F-FDG PET/CT in Advanced Melanoma Treated With Dabrafenib and Trametinib

被引：14
|
作者：
Martinez-Rodriguez, Isabel [1 ]
Garcia-Castano, Almudena [2 ]
Quirce, Remedios [1 ]
Jimenez-Bonilla, Julio [1 ]
Banzo, Ignacio [1 ]
机构：
[1] Univ Cantabria, Mol Imaging Grp IDIVAL, Marques Valdecilla Univ Hosp, Dept Nucl Med, Santander, Spain
[2] Univ Cantabria, Mol Imaging Grp IDIVAL, Marques Valdecilla Univ Hosp, Dept Oncol, Santander, Spain
来源：
CLINICAL NUCLEAR MEDICINE | 2017年 / 42卷 / 01期
关键词：
melanoma; F-18-FDG PET/CT; erythema nodosum; panniculitis; dabrafenib; trametinib; MUTATED METASTATIC MELANOMA; RANDOMIZED CONTROLLED-TRIAL; BRAF INHIBITOR; MEK INHIBITION; SURVIVAL; COMBINATION; MULTICENTER; THERAPY;
D O I：
10.1097/RLU.0000000000001448
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
We present a 35-year-old woman with left axillary mass. Histopathological analysis revealed metastatic infiltration for BRAF-mutant melanoma. F-18-FDG PET/CT showed bilateral axillary lymphadenopathy as well as bone and subcutaneous metastases. Dabrafenib (a BRAF inhibitor) and trametinib (a MEK inhibitor) combined therapy was started with a complete metabolic response established by 2 consecutive PET/CT scans. A follow-up PET/CT showed FDG uptake in several subcutaneous nodules in both distal legs, suggesting metastases. Painless cutaneous lesions were observed on physical examination, and biopsy revealed erythema nodosum-like panniculitis.
引用
收藏
页码：44 / 46
页数：3
相关论文
共 50 条
  • [1] Erythema Nodosum-Like Panniculitis in Patients With Melanoma Treated With Vemurafenib
    Sinha, Rishika
    Edmonds, Kim
    Newton-Bishop, Julia
    Gore, Martin
    Larkin, James
    Fearfield, Louise
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (19) : E320 - E321
  • [2] Metformine induces false-positive 18F-FDG PET/CT uptake
    Brihaye, Benoit
    Lidove, Olivier
    Lussato, David
    Aparicio, Thomas
    Papo, Thomas
    [J]. PRESSE MEDICALE, 2009, 38 (04): : 686 - 687
  • [3] False Negative and False Positive Findings with 18F-FDG PET/CT in Malignant Melanoma
    Liszkay, G.
    Kasler, M.
    Gilde, K.
    Fejos, Z.
    Lengyel, Z.
    Borbola, K.
    Schmidt, E.
    Borbely, K.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2010, 37 : S442 - S442
  • [4] Tuberculosis Presenting as Cutaneous Erythema Nodosum on 18F-FDG PET/CT
    Jain, Tarun Kumar
    [J]. CLINICAL NUCLEAR MEDICINE, 2019, 44 (06) : E406 - E408
  • [5] The False-Positive Finding of Left Pulmonary Kimura Disease on 18F-FDG PET/CT
    Li, Dong
    Li, Ya-Jun
    Zhan, Feng-Hua
    Dang, Chun-Jiang
    [J]. CLINICAL NUCLEAR MEDICINE, 2013, 38 (07) : 569 - 572
  • [6] Diagnosis of unknown sarcoidosis associated to erythema nodosum with 18F-FDG PET/CT
    Rampin, L.
    Musto, A.
    Marzola, M. C.
    Tadayyon, S.
    Ferretti, A.
    Chondrogiannis, S.
    Grassetto, G.
    Rubello, D.
    [J]. REVISTA ESPANOLA DE MEDICINA NUCLEAR E IMAGEN MOLECULAR, 2013, 32 (03): : 190 - 192
  • [7] Lymphangiography causes false-positive findings on 18F-FDG PET imaging
    Reinhardt, MJ
    Technau-Ihling, K
    Altehoefer, C
    Vogelgesang, D
    Krause, TM
    [J]. ANTICANCER RESEARCH, 2003, 23 (3C) : 2941 - 2944
  • [8] Acute Toxoplasmosis Mimicking Melanoma Metastases: Review of Conditions Causing False-Positive Results on 18F-FDG PET/CT
    Ivanova, K.
    Glatz, K.
    Zippelius, A.
    Nicolas, G.
    Itin, P.
    [J]. DERMATOLOGY, 2012, 225 (04) : 349 - 353
  • [9] False positive 18F-FDG PET/CT due to gynaecomastia
    R. Ramtahalsing
    A. I. J. Arens
    R. F. A. Vliegen
    G. J. J. Teule
    P. L. A. van den Ende
    R. G. H. Beets-Tan
    [J]. European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34 : 614 - 614
  • [10] False positive 18F-FDG PET/CT due to gynaecomastia
    Ramtahalsing, R.
    Arens, A. I. J.
    Vliegen, R. F. A.
    Teule, G. J. J.
    van den Ende, P. L. A.
    Beets-Tan, R. G. H.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2007, 34 (04) : 614 - 614
12345