Structural Basis of Prion Protein Conformation Conversion Inhibition

被引：0
|
作者：
Baral, P. [1 ]
Swayampakula, M. [1 ]
Rout, M. [1 ]
Spyracopoulos, L. [1 ]
Aguzzi, A. [2 ]
James, M. [1 ]
机构：
[1] Univ Alberta, Dept Biochem, Edmonton, AB, Canada
[2] Univ Hosp Zurich, Inst Neuropathol, Dept Pathol, Zurich, Switzerland
来源：
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES | 2014年 / 70卷
关键词：
Prion Protein; Phenothiazine compounds; Initiator Motifs;
D O I：
10.1107/S2053273314091876
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
MS53.P10
引用
收藏
页码：C812 / C812
页数：1
相关论文
共 50 条
  • [1] Early structural features in mammalian prion conformation conversion
    Legname, Giuseppe
    [J]. PRION, 2012, 6 (01) : 37 - 39
  • [2] Structural Underpinnings of Prion Protein Conversion
    Apostol, Marcin I.
    Surewicz, Witold K.
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (21)
  • [3] Structural Basis of Prion Inhibition by Phenothiazine Compounds
    Baral, Pravas Kumar
    Swayampakula, Mridula
    Rout, Manoj Kumar
    Kav, Nat N. V.
    Spyracopoulos, Leo
    Aguzzi, Adriano
    James, Michael N. G.
    [J]. STRUCTURE, 2014, 22 (02) : 291 - 303
  • [4] The challenge of structural understanding of prion protein conversion and prion propagation
    Surewicz, Witold K.
    [J]. PRION, 2012, 6 : 2 - 2
  • [5] Inhibition of prion-protein conversion: a therapeutic tool?
    Head, MW
    Ironside, JW
    [J]. TRENDS IN MICROBIOLOGY, 2000, 8 (01) : 6 - 8
  • [6] Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency
    Hannaoui, Samia
    Amidian, Sara
    Cheng, Yo Ching
    Velasquez, Camilo Duque
    Dorosh, Lyudmyla
    Law, Sampson
    Telling, Glenn
    Stepanova, Maria
    McKenzie, Debbie
    Wille, Holger
    Gilch, Sabine
    [J]. PLOS PATHOGENS, 2017, 13 (08)
  • [7] The structural and spectroscopic basis for modelling prion protein interactions
    Warwicker, J
    Cole, C
    [J]. SPECTROSCOPY-AN INTERNATIONAL JOURNAL, 2001, 15 (3-4): : 151 - 159
  • [8] Structural basis for nucleic acid binding to the prion protein
    Cordeiro, Y
    Lima, LM
    Marques, A
    Oliveira, C
    Tinoco, L
    Sampath, S
    Foguel, D
    Torriani, I
    Caughey, B
    Silva, J
    [J]. FASEB JOURNAL, 2006, 20 (04): : A95 - A95
  • [9] Prion Protein and Its Conformational Conversion: A Structural Perspective
    Surewicz, Witold K.
    Apostol, Marcin I.
    [J]. PRION PROTEINS, 2011, 305 : 135 - 167
  • [10] Structural investigation of prion protein conversion induced by oxidative stress
    Redecke, Lars
    Sommer, Anne
    Elmallah, Mohammed
    Rehders, Dirk
    Kikhney, Alexey
    Binder, Stephan
    Svergun, Dmitri
    Ruebhausen, Michael
    Betzel, Christian
    [J]. PRION, 2012, 6 : 31 - 32
12345