Serum levels of selenium, manganese, copper, and iron in colorectal cancer patients

被引:45
|
作者
Milde, D
Novák, O
Stuzka, V
Vyslouzil, K
Machácek, J
机构
[1] Palacky Univ, Dept Analyt Chem, Olomouc 77146, Czech Republic
[2] Teaching Hosp, Olomouc 77520, Czech Republic
关键词
selenium; manganese; copper; iron; serum levels; colorectal cancer; atomic absorption spectrometry;
D O I
10.1385/BTER:79:2:107
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This article describes a study in which four trace elements (Se, Mn, Cu, and Fe) were analyzed in the blood serum of the patients with colorectal cancer from the Moravian region of the Czech Republic. Atomic absorption spectrometry with graphite furnace atomization was used for analysis of selenium and manganese and with flame atomization for analysis of copper and iron. The observed serum concentrations in adenocarcinoma colorectal patients of selenium were significantly lower (41.8 +/- 11.6 mug/L) and those of manganese (16.3 +/- 4.5 mug/L) and iron (2.89 +/- 1.23 mg/L) were significantly higher as compared to the age-matched control group. Copper serum content (0.95 +/- 0.28 mg/L) did not significantly differ as compared to healthy population.
引用
收藏
页码:107 / 114
页数:8
相关论文
共 50 条
  • [1] Serum levels of selenium, manganese, copper, and iron in colorectal cancer patients
    David Milde
    Ondrej Novák
    Vaclav Stuzka
    Kamil Vyslouzil
    Jindrich Machácek
    Biological Trace Element Research, 2001, 79 : 107 - 114
  • [2] Serum Levels of Selenium, Zinc, Copper, Manganese, and Iron in Prostate Cancer Patients
    Saleh, Saleh A. K.
    Adly, Heba M.
    Abdelkhaliq, Altaf A.
    Nassir, Anmar M.
    CURRENT UROLOGY, 2020, 14 (01) : 44 - 49
  • [3] Serum levels of zinc, copper, selenium and glutathione peroxidase in the different groups of colorectal cancer patients
    Al-ansari, Raghad F.
    AL-Gebori, Abdulnasser M.
    Sulaiman, Ghassan M.
    CASPIAN JOURNAL OF INTERNAL MEDICINE, 2020, 11 (04) : 384 - 390
  • [4] SELENIUM, ZINC, IRON AND COPPER LEVELS IN SERUM OF PATIENTS WITH ARTERIAL AND VENOUS LEG ULCERS
    AGREN, MS
    STROMBERG, HE
    RINDBY, A
    HALLMANS, G
    ACTA DERMATO-VENEREOLOGICA, 1986, 66 (03) : 237 - 240
  • [5] Serum Copper and Zinc Levels Among Iranian Colorectal Cancer Patients
    Zahra Khoshdel
    Fakhraddin Naghibalhossaini
    Kourosh Abdollahi
    Shahla Shojaei
    Mostafa Moradi
    Mahyar Malekzadeh
    Biological Trace Element Research, 2016, 170 : 294 - 299
  • [6] Serum Copper and Zinc Levels Among Iranian Colorectal Cancer Patients
    Khoshdel, Zahra
    Naghibalhossaini, Fakhraddin
    Abdollahi, Kourosh
    Shojaei, Shahla
    Moradi, Mostafa
    Malekzadeh, Mahyar
    BIOLOGICAL TRACE ELEMENT RESEARCH, 2016, 170 (02) : 294 - 299
  • [7] PHYSIOLOGICAL VARIATIONS OF SERUM LEVELS OF COPPER, ZINC, IRON, MANGANESE
    FAVIER, A
    RUFFIEUX, D
    ANNALES DE BIOLOGIE CLINIQUE, 1982, 40 (04) : 451 - 451
  • [8] PHYSIOLOGICAL VARIATIONS OF SERUM LEVELS OF COPPER, ZINC, IRON AND MANGANESE
    FAVIER, A
    RUFFIEUX, D
    BIOMEDICINE & PHARMACOTHERAPY, 1983, 37 (9-10) : 462 - 466
  • [9] Plasma manganese, selenium, zinc, copper, and iron concentrations in patients with schizophrenia
    Yanik, M
    Kocyigit, A
    Tutkun, H
    Vural, H
    Herken, H
    BIOLOGICAL TRACE ELEMENT RESEARCH, 2004, 98 (02) : 109 - 117
  • [10] Plasma manganese, selenium, zinc, copper, and iron concentrations in patients with schizophrenia
    Medaim Yanik
    Abdurrahim Kocyigit
    Hamdi Tutkun
    Huseyin Vural
    Hasan Herken
    Biological Trace Element Research, 2004, 98 : 109 - 117