structured population;
cell cycle;
first order partial differential equation with delays;
stem cells;
delay;
aplastic anemia;
instability;
D O I:
暂无
中图分类号:
O29 [应用数学];
学科分类号:
070104 ;
摘要:
This paper analyses the behavior of the solutions of a model of cells that are capable of simultaneous proliferation and maturation. This model is described by a first-order singular partial differential system with a retardation of the maturation variable and a time delay. Both delays are due to cell replication. We prove that uniqueness and asymptotic behavior of solutions depend only on cells with small maturity (stem cells).