Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study

被引:10
|
作者
Gomes, Marilia B.
Tang, Fengming
Chen, Hungta
Cid-Ruzafa, Javier
Fenici, Peter
Khunti, Kamlesh
Rathmann, Wolfgang
Shestakova, Marina V.
Surmont, Filip
Watada, Hirotaka
Medina, Jesus
Shimomura, Iichiro
Saraiva, Gabriela Luporini
Cooper, Andrew
Nicolucci, Antonio
机构
[1] Department of Medicine, Diabetes Unit, Rio de Janeiro State University, Rio de Janeiro
[2] Saint Luke’s Mid America Heart Institute, Kansas City, MO
[3] Medical/Payer Evidence Statistics, BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, MD
[4] Barcelona, Evidera
[5] BioPharmaceuticals Medical, AstraZeneca, Cambridge
[6] Primary Care Diabetes and Vascular Medicine, University of Leicester, Leicester
[7] Institute for Biometrics and Epidemiology, German Diabetes Centre, Düsseldorf
[8] Endocrinology Research Centre, Diabetes Institute, Moscow
[9] BioPharmaceuticals Medical, AstraZeneca, Luton
[10] Graduate School of Medicine, Juntendo University, Tokyo
[11] BioPharmaceuticals Medical, AstraZeneca, Madrid
[12] Graduate School of Medicine, Osaka University, Osaka
[13] Centre for Outcomes Research and Clinical Epidemiology, Pescara
来源
基金
日本科学技术振兴机构;
关键词
type; 2; diabetes; observational study; socioeconomic factors; glycemic control; glucose-lowering drug; HEALTH; COMPLICATIONS; DETERMINANTS; RATIONALE; POSITION; OUTCOMES; ADULTS; CARE;
D O I
10.3389/fendo.2022.831676
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
DISCOVER is a 3-year observational study program of 15,983 people with type 2 diabetes initiating second-line glucose-lowering therapy in 38 countries. We investigated the association between socioeconomic status and both the availability of a baseline glycated hemoglobin (HbA1c) measurement and poor glycemic control (HbA1c level >= 9.0%) in participants enrolled in DISCOVER. Factors associated with a lack of baseline HbA1c measurement or an HbA1c level >= 9.0% were assessed using three-level hierarchical logistic models. Overall, 19.1% of participants did not have a baseline HbA1c measurement recorded. Lower-middle country income (vs. high) and primary/no formal education (vs. university education) were independently associated with a reduced likelihood of having a baseline HbA1c measurement (odds ratio [95% confidence interval]: 0.11 [0.03-0.49] and 0.81 [0.66-0.98], respectively. Of the participants with an available HbA1c measurement, 26.9% had an HbA1c level >= 9.0%; 68.7% of these individuals were from lower- or upper-middle-income countries. Factors associated with an increased likelihood of poor glycemic control included low country income, treatment at a site with public and/or governmental funding (vs. private funding) and having public or no health insurance (vs. private). A substantial proportion of DISCOVER participants did not have an HbA1c measurement; more than one-quarter of these participants had poorly controlled type 2 diabetes. Both individual- and country-level socioeconomic factors are associated with the quality of care regarding glycemic control. Awareness of these factors could help improve the management of patients with type 2 diabetes.
引用
收藏
页数:9
相关论文
共 50 条
  • [1] Socioeconomic factors associated with poor glycaemic control (HbA1c≥9.0%) in people with type 2 diabetes: the DISCOVER study
    Gomes, M.
    Tang, F.
    Chen, H.
    Cid-Ruzafa, J.
    Fenici, P.
    Khunti, K.
    Pocock, S.
    Rathmann, W.
    Shestakova, M. V.
    Surmont, F.
    Watada, H.
    Medina, J.
    Shimomura, I.
    Saraiva, G. Luporini
    Nicolucci, A.
    DIABETOLOGIA, 2019, 62 : S396 - S396
  • [2] Socioeconomic Factors Associated with Poor Glycemic Control in People with Type 2 Diabetes: The DISCOVER Study
    Gomes, Marilia B.
    Tang, Fengming
    Chen, Hungta
    Cid-Ruzafa, Javier
    Fenici, Peter
    Khunti, Kamlesh
    Pocock, Stuart
    Rathmann, Wolfgang
    Shestakova, Marina V.
    Surmont, Filip
    Watada, Hirotaka
    Medina, Jesus
    Sadikot, Shaukat M.
    Shimomura, Iichiro
    Saraiva, Gabriela Luporini
    Nicolucci, Antonio
    DIABETES, 2019, 68
  • [3] Change in HbA1c associated with treatment intensification among patients with type 2 diabetes and poor glycemic control
    Fu, Alex Z.
    Sheehan, John J.
    CURRENT MEDICAL RESEARCH AND OPINION, 2017, 33 (05) : 853 - 858
  • [4] Individualised HbA1c targets in people with type 2 diabetes initiating second-line therapy: the global DISCOVER study
    Khunti, K.
    Chen, H.
    Cid-Ruzafa, J.
    Fenici, P.
    Gomes, M. B.
    Hammar, N.
    Kennedy, K. F.
    Pocock, S.
    Shestakova, M. V.
    Shimomura, I.
    Surmont, F.
    Ji, L.
    DIABETOLOGIA, 2018, 61 : S175 - S175
  • [5] Glycemic Control with Tirzepatide in People with Type 2 Diabetes by Baseline HbA1c=8.5% or >8.5%
    Aleppo, Grazia
    De Block, Christophe
    Levine, Joshua A.
    Gomez-Valderas, Elisa
    Benneyworth, Brian D.
    DIABETES, 2022, 71
  • [6] Poor glycemic control in type 2 diabetes in the South of the Sahara: The issue of limited access to an HbA1c test
    Camara, Alioune
    Balde, Naby M.
    Sobngwi-Tambekou, Joelle
    Kengne, Andre P.
    Diallo, Mansour M.
    Tchatchoua, Alain P. K.
    Kake, Amadou
    Sylvie, Ngamani
    Balkau, Beverley
    Bonnet, Fabrice
    Sobngwi, Eugene
    DIABETES RESEARCH AND CLINICAL PRACTICE, 2015, 108 (01) : 187 - 192
  • [7] Individualized HbA1c Targets in People with Type 2 Diabetes Initiating Second-Line Therapy-The Global DISCOVER Study
    Khunti, Kamlesh
    Chen, Hungta
    Cid-Ruzafa, Javier
    Fenici, Peter
    Gomes, Marilia B.
    Hammar, Niklas
    Kennedy, Kevin
    Kosiborod, Mikhail
    Pocock, Stuart
    Shestakova, Marina V.
    Shimomura, Iichiro
    Surmont, Filip
    Ji, Linong
    DIABETES, 2018, 67
  • [8] HbA1c variability associated with dementia risk in people with type 2 diabetes
    Moran, Chris
    Whitmer, Rachel A.
    Dove, Zoe
    Lacy, Mary E.
    Soh, Yenee
    Tsai, Ai-Lin
    Quesenberry, Charles P.
    Karter, Andrew J.
    Adams, Alyce S.
    Gilsanz, Paola
    ALZHEIMERS & DEMENTIA, 2024, 20 (08) : 5561 - 5569
  • [9] HbA1c Trajectory and Its Associated Factors in Patients with Type 2 Diabetes
    Yu, Tzu-Yun
    Li, Tsai-Chung
    Lin, Cheng-Chieh
    DIABETES, 2016, 65 : A607 - A607
  • [10] Survival in people with type 2 diabetes as a function of HbA1c
    Balkau, Beverley
    Simon, Dominique
    LANCET, 2010, 375 (9713): : 438 - 440