The basic chemical substances of three medicinal parts from Rhododendron molle G. Don

被引:8
|
作者
Song, Zhen-Fei [1 ]
Zheng, Xiang-Wei [1 ]
Xue, Qiu-Wen [1 ]
Qin, Jia-Xu [1 ]
Fang, Xin [1 ]
Liang, Shuang [1 ]
机构
[1] Shanghai Univ Tradit Chinese Med, Engn Res Ctr Modern Preparat Technol Tradit Chine, Minist Educ, Innovat Res Inst Tradit Chinese Med, Shanghai, Peoples R China
关键词
Rhododendron Molle; medicinal parts; traceability separation; characteristic peaks; basic chemical substances;
D O I
10.1080/14786419.2021.1986710
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Rhododendron Molle G. Don belongs to Ericaceae family. As a toxic traditional Chinese medicine, its roots, flowers, and fruit are often mixed and substituted arbitrarily to treat rheumatoid arthritis in clinic. To clarify the main chemical basis of each medicinal part, and provide sufficient scientific basis for clinical application, analysis using HPLC-ELSD of the roots, flowers, and fruit from R. molle was established, and characteristic chemical constituents of them were separated by tracking. The structures were determined by NMR methods. Finally, 16, 21, and 18 compounds were obtained from the roots, flowers, and fruit, respectively. Overall, 49 compounds were obtained, of which 25 were identified for the first time in R. molle. Meanwhile, among the obtained compounds, 12, 11, and 6 characteristic peaks were identified from the roots, flowers, and fruit, respectively. Thus, the basic chemical substances of the medicinal parts of R. molle were determined initially.
引用
收藏
页码:4498 / 4501
页数:4
相关论文
共 50 条
  • [1] Studies on the Chemical Constituents of the Roots of Rhododendron Molle G. Don
    向彦妮
    张长弓
    郑亚杰
    华中科技大学学报(医学英德文版), 2004, (02) : 202 - 204
  • [2] De novo transcriptome analysis of Rhododendron molle G. Don flowers by Illumina sequencing
    Xiao, Zheng
    Su, Jiale
    Sun, Xiaobo
    Li, Chang
    He, Lisi
    Cheng, Shangping
    Liu, Xiaoqing
    GENES & GENOMICS, 2018, 40 (06) : 591 - 601
  • [3] De novo transcriptome analysis of Rhododendron molle G. Don flowers by Illumina sequencing
    Zheng Xiao
    Jiale Su
    Xiaobo Sun
    Chang Li
    Lisi He
    Shangping Cheng
    Xiaoqing Liu
    Genes & Genomics, 2018, 40 : 591 - 601
  • [4] Unlocking the potential antioxidant and anti-inflammatory activities of Rhododendron molle G. Don
    Zhang, Jin
    Liu, Jian
    Dai, Liang-Fang
    Zhang, Hong-Yi
    Chen, Min-Na
    Cai, Xian-Feng
    Xie, Jian-Kun
    Luo, Xiang-Dong
    PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 32 (05) : 2375 - 2383
  • [5] Selection of Reliable Reference Genes for Gene Expression Studies on Rhododendron molle G. Don
    Xiao, Zheng
    Sun, Xiaobo
    Liu, Xiaoqing
    Li, Chang
    He, Lisi
    Chen, Shangping
    Su, Jiale
    FRONTIERS IN PLANT SCIENCE, 2016, 7
  • [6] Studies on the chemical constituents of the roots ofRhododendron molle G. don
    Xiang Yanni
    Zhang Changgong
    Zheng Yajie
    Current Medical Science, 2004, 24 (2) : 202 - 204
  • [7] Evaluation of Rhodojaponin III from Rhododendron molle G. Don on oral antinociceptive activity, mechanism of action, and subacute toxicity in rodents*
    Yang, Jian
    Yang, Qingyun
    Zhao, Jingyi
    Sun, Shuigen
    Liu, Minchen
    Wang, Yuan
    Feng, Yi
    Zhang, Jiquan
    JOURNAL OF ETHNOPHARMACOLOGY, 2022, 294
  • [8] Anti-rheumatoid arthritis potential of Rhododendron molle G. Don leaf extract in adjuvant induced arthritis rats
    Luo, Yuqiang
    Shen, Yu
    Zong, Luye
    Xie, Jiankun
    Dai, Liangfang
    Luo, Xiangdong
    JOURNAL OF ETHNOPHARMACOLOGY, 2023, 307
  • [9] Three new dimeric diterpenes from Rhododendron molle
    Shuai-Zhen Zhou
    Chun-Ping Tang
    Chang-Qiang Ke
    Sheng Yao
    Ge Lin
    Yang Ye
    ChineseChemicalLetters, 2017, 28 (06) : 1205 - 1209
  • [10] Potential Anti-Inflammatory Components of Rhododendron molle G. Don Leaf Extracts in LPS-Induced RAW 264.7
    Luo, Yuqiang
    Wu, Decai
    Zong, Luye
    Shen, Yu
    Dai, Liangfang
    Luo, Xiangdong
    CHEMISTRY & BIODIVERSITY, 2023, 20 (04)