Genome Sequence of the Fungus Glarea lozoyensis: the First Genome Sequence of a Species from the Helotiaceae Family

被引：17
|
作者：
Youssar, Loubna [1 ]
Gruening, Bjoern Andreas [2 ]
Erxleben, Anika [2 ]
Guenther, Stefan [2 ]
Huettel, Wolfgang [1 ]
机构：
[1] Univ Freiburg, Inst Pharmaceut Sci Pharmaceut & Med Chem, D-79106 Freiburg, Germany
[2] Univ Freiburg, Inst Pharmaceut Sci, D-79106 Freiburg, Germany
来源：
EUKARYOTIC CELL | 2012年 / 11卷 / 02期
关键词：
ZALERION-ARBORICOLA; IDENTIFICATION; BIOSYNTHESIS; CLUSTERS;
D O I：
10.1128/EC.05302-11
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The anamorphic fungus Glarea lozoyensis mutant strain 74030 is an overproducer of pneumocandin B-0, which is chemically converted into Cancidas, a potent antibiotic against clinically important fungal pathogens. Pneumocandins are acylated, cyclic hexapeptides with unusual hydroxylated amino acids. With the Glarea lozoyensis genome, the first species from the large polyphyletic family Helotiaceae has been sequenced.
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页码：250 / 250
页数：1
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