Life events and the risk of breast cancer: A case-control study

被引：32
|
作者：
Ginsberg, A [1 ]
Price, S [1 ]
Ingram, D [1 ]
Nottage, E [1 ]
机构：
[1] UNIV WESTERN AUSTRALIA,QUEEN ELIZABETH II MED CTR,DEPT SURG,NEDLANDS,WA 6009,AUSTRALIA
来源：
EUROPEAN JOURNAL OF CANCER | 1996年 / 32A卷 / 12期
关键词：
breast cancer; stress; life events;
D O I：
10.1016/S0959-8049(96)00275-4
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A case-control study was undertaken to investigate the possibility of an association between stressful life events and the development of breast cancer. Ninety-nine breast cancer cases, and 99 controls matched by age and area of residence, completed a life events inventory to measure life change and distress scores over a 2-year and a 10-year period. Study subjects were also interviewed to establish potential breast cancer risk factors; their height and weight were measured; they completed a food frequency questionnaire and provided a fasting blood sample for hormonal assay. After adjusting for potential confounders, women with a 10-year life change score greater than 210 (i.e. the highest quartile) had 4.67 times the risk of developing breast cancer, compared with those in the lowest quartile (P < 0.05). Copyright (C) 1996 Elsevier Science Ltd
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页码：2049 / 2052
页数：4
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