Mathematical modelling of ethanol production from glucose/xylose mixtures by recombinant Zymomonas mobilis

被引：69
|
作者：
Leksawasdi, N [1 ]
Joachimsthal, EL [1 ]
Rogers, PL [1 ]
机构：
[1] Univ New S Wales, Dept Biotechnol, Sydney, NSW 2052, Australia
来源：
BIOTECHNOLOGY LETTERS | 2001年 / 23卷 / 13期
关键词：
ethanol; modelling; recombinant Zymomonas mobilis;
D O I：
10.1023/A:1010599530577
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A model has been developed for the fermentation of mixtures of glucose and xylose by recombinant Zymomonas mobilis strain ZM4(pZB5), containing additional genes for xylose assimilation and metabolism. A two-substrate model based on substrate limitation, substrate inhibition, and product (ethanol) inhibition was evaluated, and experimental data was compared with model simulations using a Microsoft EXCEL based program and methods of statistical analysis for error minimization. From the results it was established that the model provides good predictions of experimental batch culture data for 25/25, 50/50, and 65/65 g l(-1) glucose/xylose media.
引用
收藏
页码：1087 / 1093
页数：7
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