Anti-inflammatory and cytotoxic cycloartanes from guayule (Parthenium argentatum)

The need for the discovery and development of new pharmaceuticals for the treatment of cancer demands that all approaches to drug discovery should be exploited. Among the possible approaches, the one from natural products has made many unique and vital contributions to drug discovery. This mini review focuses on researches made in our laboratory on cycloartanes isolated from Parthenium argentatum, as well as some of its derivatives, in order to obtain potential anti-inflammatory and anti-cancer agents.