Chromogranin A and other enteroendocrine markers in inflammatory bowel disease

被引：18
|
作者：
Massironi, Sara [1 ]
Zilli, Alessandra [1 ,2 ]
Cavalcoli, Federica [1 ,2 ]
Conte, Dario [1 ,2 ]
Peracchi, Maddalena [1 ,2 ]
机构：
[1] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Gastroenterol & Endoscopy Unit, Via F Sforza 35, I-20122 Milan, Italy
[2] Univ Milan, Postgrad Sch Gastroenterol, Dept Pathophysiol & Transplantat, I-20122 Milan, Italy
来源：
NEUROPEPTIDES | 2016年 / 58卷
关键词：
Chromogranin A; Enteroendocrine cell; Inflammatory bowel disease; Crohn's disease; Ulcerative colitis; VASOACTIVE-INTESTINAL-PEPTIDE; CHRONIC ULCERATIVE-COLITIS; ATYPICAL CARCINOID-TUMOR; NEUROPEPTIDE-Y NPY; SUBSTANCE-P; CROHNS-DISEASE; ION-TRANSPORT; IMMUNOREACTIVE SOMATOSTATIN; PANCREATIC-POLYPEPTIDE; GASTROINTESTINAL-TRACT;
D O I：
10.1016/j.npep.2016.01.002
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Changes in the distribution and products of enteroendocrine cells may play a role in immune activation and regulation of gut inflammation. This review aims at critically evaluating the main enteroendocrine markers in inflammatory bowel diseases (IBD). A narrative review was performed by searching inflammatory bowel diseases and enteroendocrine biomarkers in PubMed. Relevant modifications of some enteroendocrine markers, such as Chromogranin A, and their correlation with disease activity have been reported in patients with inflammatory bowel diseases. Even if data about neuroendocrine markers are sometimes contrasting, they may be potentially useful for the diagnosis and clinical management of these patients. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：127 / 134
页数：8
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