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Univ Birmingham, Sch Med, Dept Paediat & Child Hlth, Sect Med & Mol Genet,Div Reprod & Child Hlth, Birmingham B15 2TT, W Midlands, England Univ Birmingham, Sch Med, Dept Paediat & Child Hlth, Sect Med & Mol Genet,Div Reprod & Child Hlth, Birmingham B15 2TT, W Midlands, England