Phenotypical and genetic analysis of human immunodeficiency virus (HIV-1) and subtype B isolated in Russia

被引：0

作者：

Selimova, LM ^{[1
]}

Bobkov, AF

Serebrovskaya, LV

Kravchenko, AV

Lyubaeva, YV

Kazennova, YV

Sankov, MN

Pokrovsky, VV

机构：

[1] DI Ivanovskii Virol Inst, Moscow 123098, Russia

[2] Russian Sci Educ AIDS Prevent Ctr, Moscow, Russia

来源：

VOPROSY VIRUSOLOGII | 1998年 / 43卷 / 03期

关键词：

type I human immunodeficiency virus; subtype B; isolate; phenotype; genotype; characteristics;

D O I：

暂无

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Human immunodeficiency type 1 virus env subtype B 95RU25B isolated from a Russian citizen is studied. The time course of clinical changes and immunological parameters over 5.5 years is presented. Phenotypical characteristics of the isolate were assessed by culturing in different sensitive cell cultures. Genotyping by the heteroduplex analysis and env gene sequencing were carried out. 95RU25B variant is capable of infecting a wide spectrum of cell cultures and by the type of replication can be classified with the S/L.3 group. The phenotypical properties of the isolate apparently determine the characteristic features in the primary structure of V3 loop.

引用

页码：110 / 113

页数：4

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