Preparation of Porous Hydrogels Using Blowing Agents and Application to Contact Lenses

被引:3
|
作者
Oh, Chang-Hyun [1 ]
Bae, Ju-Hyun [2 ]
Lee, Hyun-Mee [2 ]
机构
[1] Vaovis Care, Mudong Ro 226, Chang Won 51106, Gyeongnam, South Korea
[2] Daegu Catholic Univ, Coll Bio & Med Sci, Dept Optometry & Vis Sci, Hayang Ro 13-13, Gyongsan 38430, Gyeongbuk, South Korea
基金
新加坡国家研究基金会;
关键词
contact lens; porous hydrogel; blowing agent; wettability; oxygen permeability; INTRAOCULAR-LENS;
D O I
10.7317/pk.2022.46.1.47
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
This study aims to confirm the applicability of a contact lens by manufacturing a high-functional porous hydrogel containing a blowing agent and examining its properties. In addition, the physical properties according to the type and content of the blowing agent in the hydrogel were compared. Hydrogel contact lenses were prepared using 1% and 3% sodium carbonate, sodium bicarbonate, potassium carbonate and potassium bicarbonate as blowing agent, respectively. Light transmittance, water content, refractive index, oxygen permeability, contact angle, protein adsorption were measured for physical and chemical properties. As the amount of blowing agent increased, the water content, wettability, and oxygen permeability increased, but the refractive index and tensile strength decreased. The adsorption amount of protein also decreased as the amount of blowing agent increased. The hydrogel added with the foaming agent maintained the basic optical properties of the contact lens, and it was confirmed that it could be applied to the contact lens because it was very excellent in moisture content, oxygen permeability, and wettability.
引用
收藏
页码:47 / 55
页数:9
相关论文
共 50 条
  • [1] PROTEIN MIGRATION THROUGH HYDROGELS - A TOOL FOR MEASURING POROSITY - APPLICATION TO HYDROGELS USED AS CONTACT-LENSES
    GACHON, AM
    BILBAULT, T
    DASTUGUE, B
    ANALYTICAL BIOCHEMISTRY, 1986, 157 (02) : 249 - 255
  • [2] POLYMERIC HYDROGELS FOR SOFT CONTACT-LENSES
    SINGH, J
    AGRAWAL, K
    RAY, AR
    SINGHAL, JP
    SINGH, H
    DADA, VK
    MEHTA, MR
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1992, 26 (09): : 1253 - 1257
  • [3] CONTACT-LENSES AS THERAPEUTIC AGENTS
    KILP, H
    DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 1975, 100 (50) : 2572 - 2574
  • [4] POROUS CONTACT-LENSES IN APHAKIA
    KEMMETMULLER, H
    KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE, 1973, 163 (03) : 331 - 337
  • [5] Bioinspired hydrogels for drug-eluting contact lenses
    Alvarez-Lorenzo, Carmen
    Anguiano-Igea, Soledad
    Varela-Garcia, Angela
    Vivero-Lopez, Maria
    Concheiro, Angel
    ACTA BIOMATERIALIA, 2019, 84 : 49 - 62
  • [6] SYNTHESIS AND CHARACTERIZATION OF HYDROGELS AS MATERIAL FOR CONTACT-LENSES
    KOSSMEHL, G
    KLAUS, N
    SCHAFER, H
    ANGEWANDTE MAKROMOLEKULARE CHEMIE, 1984, 123 (AUG): : 241 - 259
  • [7] Templated Hydrogels for Combination Devices: Therapeutic Contact Lenses
    Ali, Maryam
    Vaughan, Asa D.
    Zhang, Jeney
    Venkatesh, Sid
    Byrne, Mark E.
    2009 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-20, 2009, : 242 - +
  • [8] Preparation and Characterization of Poly Dimethylsiloxane Based on Polyurethane Hydrogels with Interpenetrating Network Structure for Contact Lenses Uses
    Helaly, Fahima
    El-Sawy, Sanaa
    Hashem, Ahmad
    Mourad, Reda
    EGYPTIAN JOURNAL OF CHEMISTRY, 2018, 61 (01): : 61 - 74
  • [9] The effect of albumin and cholesterol on the biotribological behavior of hydrogels for contact lenses
    Silva, D.
    Fernandes, A. C.
    Nunes, T. G.
    Colaco, R.
    Serro, A. P.
    ACTA BIOMATERIALIA, 2015, 26 : 184 - 194
  • [10] Vat photopolymerization printing of functionalized hydrogels on commercial contact lenses
    Hisham, Muhammed
    Butt, Haider
    SCIENTIFIC REPORTS, 2024, 14 (01):