Mouse whole-body organ mapping by non-rigid registration approach

被引：5

作者：

Xiao, Di ^{[1
]}

Zahra, David ^{[2
]}

Bourgeat, Pierrick ^{[1
]}

Berghofer, Paula ^{[2
]}

Tamayo, Oscar Acosta ^{[1
,3
]}

Green, Heather ^{[2
]}

Gregoire, Marie Claude ^{[2
]}

Salvado, Olivier ^{[1
]}

机构：

[1] CSIRO, Australian E Hlth Res Ctr, Level 5,UQ Hlth Sci Bldg 901-16, Herston, Qld 4029, Australia

[2] ANSTO, LifeSci, Sydney, NSW 2232, Australia

[3] Univ Rennes 1, LTSI, Rennes, France

来源：

MEDICAL IMAGING 2011: BIOMEDICAL APPLICATIONS IN MOLECULAR, STRUCTURAL, AND FUNCTIONAL IMAGING | 2011年 / 7965卷

关键词：

Non-rigid registration; mouse whole-body organ mapping; CT; ATLAS;

D O I：

10.1117/12.877921

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Automatic small animal whole-body organ registration is challenging because of subject's joint structure, posture and position difference and loss of reference features. In this paper, an improved 3D shape context based non-rigid registration method is applied for mouse whole-body skeleton registration and lung registration. A geodesic path based non-rigid registration method is proposed for mouse torso skin registration. Based on the above registration methods, a novel non-rigid registration framework is proposed for mouse whole-body organ mapping from an atlas to new scanned CT data. A preliminary experiment was performed to test the method on lung and skin registration. A whole-body organ mapping was performed on three target data and the selected organs were compared with the manual outlining results. The robust of the method has been demonstrated.

引用

页数：7

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