Modulation of brain activities by hierarchical processing: A high-density ERP study

The present study investigated how attention to global or local levels of hierarchical patterns modulates brain activities by recording high-density event-related brain potentials (ERPs) evoked by hierarchical stimuli. 120-channel recordings of ERPs were obtained from subjects while they detected targets at global or local levels of hierarchical stimuli displayed in the left or the right visual field. We found that attention to local stimulus features enhanced posterior P1 and N2 components, with the N2 enhancement showing a left hemisphere predominance regardless of stimulus positions. Difference was also seen in the distribution of the frontal P2. Reaction times were slowed when global and local levels of stimuli were incompatible, and an interference effect was observed on anterior N2 amplitudes and latencies. Three-dimensional current distributions showed common sources over the posterior cortex between 80-230 ms and a contralateral frontal source between 300-400 ms for global and local conditions. However, an additional ipsilateral frontal focus between 230-350 ms was found specially for local processing. The results corroborate the findings of previous ERP studies, and suggest that the frontal lobe is particularly important for the selective processing of local parts of a global structure.