Synthesis and fungicidal activities of 4,5-dihydro-7H-pyrano[3,4-c]isoxazole derivatives

被引：7
|
作者：
Kim, HJ [1 ]
Jang, JY
Chung, KJ
Lee, JH
机构：
[1] Chonnam Natl Univ, Dept Chem Technol, Kwangju 500757, South Korea
[2] Korea Res Inst Chem Technol, Div Bioorgan, Daejon 305606, South Korea
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1999年 / 63卷 / 03期
关键词：
pyrano[3,4-c]isoxazole; fungicidal activity; plant pathogen; rice blast; wheat leaf rust;
D O I：
10.1271/bbb.63.494
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
4,5-Dihydro-7H-pyrano[3,4-c]isoxazoles (II and III) with an a-chlorophenyl or p-chlorophenyl group at C-7 were synthesized and the effect of substitution at C-3 of II and III on fungicidal activity was investigated in vivo. When the substituent at C-3 of II and III was CH2Br, CH = NOMe, CH = NOEt or CH = NO-allyl, the fungicidal effect was significant and selectively high on wheat leaf rust and barley powdery mildew at 250 ppm. Compound IId with the CH2Br substituent at C-7 showed high fungicidal activity against rice blast, providing more than 90% control of the disease at 2 ppm.
引用
收藏
页码：494 / 499
页数：6
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