Two New Pentacyclic Triterpenoids from Centella asiatica

被引：9
|
作者：
Weng, Xiao-Xiang [1 ]
Zhang, Jing [1 ]
Gao, Wen [1 ]
Cheng, Liang [1 ]
Shao, Yan [1 ]
Kong, De-Yun [1 ]
机构：
[1] Shanghai Inst Pharmaceut Ind, Dept Chinese Tradit Med, Shanghai 200040, Peoples R China
来源：
HELVETICA CHIMICA ACTA | 2012年 / 95卷 / 02期
关键词：
Centella asiatica; Centellosides D and E; Cytotoxic activity; Triterpenoids; Glycosides; GLYCOSIDES; OLEANANE; SAPONIN;
D O I：
10.1002/hlca.201100287
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Two new pentacyclic triterpenoids, named centelloside D (1) and centelloside E (9), together with the seven known compounds 28, were isolated from the whole plants of Centella asiatica. Compound 5 was reported for the first time from this genus. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D- and 2D-NMR, and HR-MS experiments, and by comparison with literature data. Compounds 14, 6, and 8 did not show any cytotoxicity against L929 (mouse embryonic fibroblast).
引用
收藏
页码：255 / 260
页数：6
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