A Handheld Imaging Probe for Acoustic Angiography With an Ultrawideband Capacitive Micromachined Ultrasonic Transducer (CMUT) Array

被引:7
|
作者
Sanders, Jean L. [1 ]
Biliroglu, Ali Onder [1 ]
Newsome, Isabel G. [2 ,3 ]
Adelegan, Oluwafemi J. [1 ]
Yamaner, Feysel Yalcin [1 ]
Dayton, Paul A. [2 ,3 ]
Oralkan, Omer [1 ]
机构
[1] North Carolina State Univ, Dept Elect & Comp Engn, Raleigh, NC 27606 USA
[2] Univ N Carolina, Joint Dept Biomed Engn, Chapel Hill, NC 27599 USA
[3] North Carolina State Univ, Chapel Hill, NC 27599 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
Probes; Imaging; Acoustics; Bandwidth; Angiography; Frequency control; Electrodes; Acoustic angiography (AA); alternate amplitude modulation (aAM); capacitive micromachined ultrasonic transducer (CMUT); glass substrate; handheld ultrasound probe; harmonic ultrasound imaging; ultrawideband (UWB) array; MICROBUBBLE CONTRAST AGENTS; IN-VITRO; DESIGN; RESOLUTION; OPTIMIZATION; ANGIOGENESIS; FABRICATION; MEMBRANES; RATIO;
D O I
10.1109/TUFFC.2022.3172566
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
This article presents an imaging probe with a 256-element ultrawideband (UWB) 1-D capacitive micromachined ultrasonic transducer (CMUT) array designed for acoustic angiography (AA). This array was fabricated on a borosilicate glass wafer with a reduced bottom electrode and an additional central plate mass to achieve the broad bandwidth. A custom 256-channel handheld probe was designed and implemented with integrated low-noise amplifiers and supporting power circuitry. This probe was used to characterize the UWB CMUT, which has a functional 3-dB frequency band from 3.5 to 23.5 MHz. A mechanical index (MI) of 0.33 was achieved at 3.5 MHz at a depth of 11 mm. These promising measurements are then combined to demonstrate AA. The use of alternate amplitude modulation (aAM) combined with a frequency analysis of the measured transmit signal demonstrates the suitability of the UWB CMUT for AA. This is achieved by measuring only a low level of unwanted high-frequency harmonics in both the transmit signal and the reconstructed image in the areas other than the contrast bubbles.
引用
收藏
页码:2318 / 2330
页数:13
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