Social phobia in immune-mediated inflammatory diseases

被引:6
|
作者
Reinhorn, Ian M. [1 ]
Bernstein, Charles N. [2 ]
Graff, Lesley A. [3 ]
Patten, Scott B. [4 ]
Sareen, Jitender [5 ]
Fisk, John D. [6 ,7 ,8 ]
Bolton, James M. [5 ,9 ]
Hitchon, Carol [2 ]
Marrie, Ruth Ann [2 ,9 ]
Walker, John R.
Singer, Alexander
Lix, Lisa M.
Hitchon, Carol A.
El-Gabalawy, Renee
Katz, Alan
Graff, Lesley
Berrigan, Lindsay
Zarychanski, Ryan
Peschken, Christine
Marriott, James
机构
[1] Univ Manitoba, Rady Fac Hlth Sci, Winnipeg, MB, Canada
[2] Univ Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Internal Med, Winnipeg, MB, Canada
[3] Univ Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Clin Hlth Psychol, Winnipeg, MB, Canada
[4] Univ Calgary, Cumming Sch Med, Dept Community Hlth Sci & Psychiat, Calgary, AB, Canada
[5] Univ Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Psychiat, Winnipeg, MB, Canada
[6] Dalhousie Univ, Dept Psychiat, Nova Scotia Hlth Author, Halifax, NS, Canada
[7] Dalhousie Univ, Dept Psychol & Neurosci, Halifax, NS, Canada
[8] Dalhousie Univ, Dept Med, Halifax, NS, Canada
[9] Univ Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Community Hlth Sci, Winnipeg, MB, Canada
基金
加拿大健康研究院;
关键词
Social phobia; Immune-mediated inflammatory disease; Anxiety; Multiple sclerosis; Inflammatory bowel disease; Rheumatoid arthritis; MULTIPLE-SCLEROSIS; ANXIETY DISORDERS; PSYCHIATRIC-DISORDERS; DIAGNOSTIC-CRITERIA; AMERICAN-COLLEGE; INVENTORY SPIN; DEPRESSION; COMORBIDITY; VALIDITY; RELIABILITY;
D O I
10.1016/j.jpsychores.2019.109890
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: Immune-mediated inflammatory diseases (IMID) such as multiple sclerosis (MS), inflammatory bowel disease (IBD) and rheumatoid arthritis (RA) are associated with a high prevalence of psychiatric comorbidity but little is known about the prevalence of social phobia in IMID, or the factors associated with social phobia. We aimed to determine the prevalence of social phobia in MS, IBD and RA, and the factors associated with social phobia in these IMID. Methods: We obtained data from the enrollment visit of a cohort study in IMID of whom 654 participants were eligible for this analysis (MS: 254, IBD: 247, RA: 153). Each participant underwent a semi-structured psychiatric interview which identified depression and anxiety disorders including social phobia (lifetime and current), an assessment of disease activity, and reported sociodemographic information. Results: Overall, 12.8% of participants had a lifetime diagnosis of social phobia (MS: 10.2%, IBD: 13.0%, RA: 17.0%). Social phobia was associated with younger age (OR 0.98; 0.97-1.00), having a high school education or less (OR 1.78; 1.08-2.91), comorbid major depressive disorder (OR 2.79; 1.63-4.78) and comorbid generalized anxiety disorder (OR 2.56; 1.30-5.05). Persons with RA had increased odds of having social phobia as compared to persons with MS (OR 2.26; 1.14-4.48) but not IBD. Conclusion: Persons with IMIDs have a relatively high lifetime prevalence of social phobia, exceeding that reported for the Canadian general population. Strategies aimed at early detection, and effective clinical management of social phobia in IMID are warranted.
引用
收藏
页数:7
相关论文
共 50 条
  • [1] Genetics of immune-mediated inflammatory diseases
    David, T.
    Ling, S. F.
    Barton, A.
    [J]. CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2018, 193 (01): : 3 - 12
  • [2] Reframing Immune-Mediated Inflammatory Diseases
    Boutrid, Nada
    Rahmoune, Hakim
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (21):
  • [3] Inflammatory and Immune-Mediated Cutaneous Diseases
    Quaresma, Juarez A. S.
    Sotto, Mirian N.
    Balato, Anna
    [J]. MEDIATORS OF INFLAMMATION, 2017, 2017
  • [4] Immune-mediated inflammatory diseases and psoriasis
    Delaporte, E.
    [J]. ANNALES DE DERMATOLOGIE ET DE VENEREOLOGIE, 2008, 135 : S269 - S274
  • [5] Adiponectin in inflammatory and immune-mediated diseases
    Fantuzzi, Giamila
    [J]. CYTOKINE, 2013, 64 (01) : 1 - 10
  • [6] Immune monitoring and treatment in immune-mediated inflammatory diseases
    Femke van Wijk
    Marjolein de Bruin
    Helen Leavis
    Stefan Nierkens
    [J]. Nature Communications, 13
  • [7] Immune monitoring and treatment in immune-mediated inflammatory diseases
    van Wijk, Femke
    de Bruin, Marjolein
    Leavis, Helen
    Nierkens, Stefan
    [J]. NATURE COMMUNICATIONS, 2022, 13 (01)
  • [8] Psychiatric comorbidity in immune-mediated inflammatory diseases
    Marrie, Ruth Ann
    Bernstein, Charles N.
    [J]. WORLD PSYCHIATRY, 2021, 20 (02) : 298 - 299
  • [9] The Gut Microbiota in Immune-Mediated Inflammatory Diseases
    Forbes, Jessica D.
    Van Domselaar, Gary
    Bernstein, Charles N.
    [J]. FRONTIERS IN MICROBIOLOGY, 2016, 7
  • [10] The role of platelets in immune-mediated inflammatory diseases
    Scherlinger, Marc
    Richez, Christophe
    Tsokos, George C. C.
    Boilard, Eric
    Blanco, Patrick
    [J]. NATURE REVIEWS IMMUNOLOGY, 2023, 23 (08) : 495 - 510