Perturbed posttranslational polyglutamylation of the neuronal microtubule cytoskeleton causes neurodegeneration in mice and humans.

被引:0
|
作者
Magiera, M. M. [1 ]
Shashi, V. [2 ]
Bodakuntla, S. [1 ]
Ziak, J. [3 ]
Klein, D. [4 ]
Rudnik-Schoenebor, S. [5 ]
Dusl, M. [6 ]
Lacomme, S. [7 ]
Sousa, P. Catarino Marques [1 ,8 ]
Leboucher, S. [1 ]
Hausrat, T. J. [9 ]
Bosc, C. [10 ]
Andrieux, A. [10 ]
Kneussel, M. [9 ]
Landry, M. [7 ]
Calas, A. [7 ]
Martini, R. [4 ]
Balastik, M. [3 ]
Senderek, J. [6 ]
Janke, C. [1 ]
机构
[1] Inst Curie, Orsay, France
[2] Duke Univ, Med Ctr, Dept Pediat, Div Med Genet, Durham, NC 27710 USA
[3] Czech Acad Sci, Dept Mol Neurobiol, Inst Physiol, Prague, Czech Republic
[4] Univ Hosp Wurzburg, Dept Neurol, Dev Neurobiol, Wurzburg, Germany
[5] Med Univ Innsbruck, Div Human Genet, Innsbruck, Austria
[6] Ludwig Maximilian Univ Munich, Friedrich Baur Inst, Dept Neurol, Munich, Germany
[7] Univ Bordeaux, Bordeaux Imaging Ctr, Bordeaux, France
[8] Harvard Med Sch, Childrens Hosp, Boston, MA 02115 USA
[9] Univ Med Ctr Hamburg Eppendorf, Ctr Mol Neurobiol ZMNH, Hamburg, Germany
[10] Univ Grenoble Alpes, Grenoble Inst Neurosci, Grenoble, France
关键词
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
P2837
引用
收藏
页数:2
相关论文
共 5 条
  • [1] Excessive tubulin polyglutamylation causes neurodegeneration and perturbs neuronal transport
    Magiera, Maria M.
    Bodakuntla, Satish
    Ziak, Jakub
    Lacomme, Sabrina
    Sousa, Patricia Marques
    Leboucher, Sophie
    Hausrat, Torben J.
    Bosc, Christophe
    Andrieux, Annie
    Kneussel, Matthias
    Landry, Marc
    Calas, Andre
    Balastik, Martin
    Janke, Carsten
    [J]. EMBO JOURNAL, 2018, 37 (23):
  • [2] Why mice are superior to humans: Studies on mice deficient in the enzyme that causes Lowe syndrome in humans.
    Nussbaum, R
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2001, 42 (04) : S4 - S4
  • [3] Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice
    Pamela McMillan
    Jeanna Wheeler
    Rachel E. Gatlin
    Laura Taylor
    Tim Strovas
    Misa Baum
    Thomas D. Bird
    Caitlin Latimer
    C. Dirk Keene
    Brian C. Kraemer
    Nicole F. Liachko
    [J]. Acta Neuropathologica Communications, 8
  • [4] Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice
    McMillan, Pamela
    Wheeler, Jeanna
    Gatlin, Rachel E.
    Taylor, Laura
    Strovas, Tim
    Baum, Misa
    Bird, Thomas D.
    Latimer, Caitlin
    Keene, C. Dirk
    Kraemer, Brian C.
    Liachko, Nicole F.
    [J]. ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2020, 8 (01)
  • [5] Tubulin-mediated binding of human immunodeficiency virus-1 Tat to the cytoskeleton causes proteasomal-dependent degradation of microtubule-associated protein 2 and neuronal damage
    Aprea, S
    Del Valle, L
    Mameli, G
    Sawaya, BE
    Khalili, K
    Peruzzi, F
    [J]. JOURNAL OF NEUROSCIENCE, 2006, 26 (15): : 4054 - 4062