Metastatic balloon cell malignant melanoma: a case report and literature review

被引：0

作者：

Lee, Lili ^{[2
]}

Zhou, Fang ^{[2
]}

Simms, Anthony ^{[2
]}

Wieczorek, Rosemary ^{[4
]}

Fang, Yanan ^{[4
]}

Subietas-Mayol, Antonio ^{[4
]}

Wang, Beverly ^{[2
]}

Heller, Patricia

Huang, Hongying ^{[2
]}

Pei, Zhiheng ^{[2
]}

Osman, Iman ^{[3
]}

Meehan, Shane ^{[3
]}

Lee, Peng ^{[1
,2
]}

机构：

[1] NYU, Sch Med, Dept Pathol & Urol, New York Harbor Healthcare Syst, New York, NY 10010 USA

[2] NYU, Sch Med, Dept Pathol, New York, NY 10010 USA

[3] NYU, Sch Med, Dept Dermatol, New York, NY 10010 USA

[4] State Univ New York, Dept Pathol, Brooklyn, NY USA

来源：

INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY | 2011年 / 4卷 / 03期

关键词：

Malignant; melanoma; balloon cell; clear cell tumors; NEVUS;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A case of metastatic balloon cell malignant melanoma (BCMM) is presented. The balloon melanoma cells (BMC) were absent in the shave biopsy of the primary lesion and present as a minor component in the wide and deep excision. A subsequent right neck lymph node metastasis showed complete replacement of the lymph node by large, foamy cells. Though the tumor was amelanocytic and Fontana-Masson stain failed to reveal melanin, it stained positively for S-100, HMB-45, and Melan-A. Ultrastructurally, the foamy cells were characterized by cytoplasmic vacuolization and a lack of melanosomes. The differential diagnosis of metastatic balloon cell malignant melanoma is broad, and clinicopathologic correlation may play a critical role in achieving the correct diagnosis.

引用

页码：315 / 321

页数：7

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