Facile Synthesis of Quaternary α-Fluoronitriles by Cobalt-Catalyzed Hydrocyanation of Monofluoroalkenes

被引：1
|
作者：
Li, Yanlin
Cui, Ru
Wu, Tian-Rui
Wang, Xi-Sheng [1 ,2 ]
机构：
[1] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China
[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China
来源：
SYNTHESIS-STUTTGART | 2022年 / 54卷 / 07期
基金：
美国国家科学基金会;
关键词：
quaternary alpha-fluoronitriles; hydrocyanation; monofluoroalkenes; cobalt catalysis; radical; ENANTIOSELECTIVE FLUORINATION; CYANO ACETATES; DIFLUOROALKYLATION; CYANOPHOSPHONATES; CONSTRUCTION; ALKENES; OLEFINS;
D O I：
10.1055/s-0040-1719841
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An exclusively regioselective hydrocyanation of monofluoroalkenes has been developed, with which a series of aliphatic quaternary alpha-fluoronitriles were synthesized in a facile and efficient manner. This novel method is featured with mild conditions, good functional groups compatibilities, and high reactivity.
引用
收藏
页码：1775 / 1784
页数：10
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