Structural conformers of symmetry substituted resorcin[4]arenes

Methylresorcin[4]arenes in the C-2h and C-4v symmetrical chair and crown conformers, and resorcin[4]arene in the C-2v symmetrical boat conformation have been synthesized from the typical one-pot acid-catalyzed reaction and structurally characterized. Solvation of organic molecules in the crystalline state of the chair and boat isomers shows inter-resorcin[4]arene interactions held together by intermolecular hydrogen bonds involving solvate molecules. The intramolecular hydrogen bonds naturally form in the crown isomer of the substituted resorcin[4]arenes. (C) 2003 Elsevier B.V. All rights reserved.