A survey of computational methods for determining haplotypes

被引:0
|
作者
Halldórsson, BV [1 ]
Bafna, V [1 ]
Edwards, N [1 ]
Lippert, R [1 ]
Yooseph, S [1 ]
Istrail, S [1 ]
机构
[1] Celera Genom, Appl Biosyst, Informat Res, Rockville, MD 20850 USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
It is widely anticipated that the study of variation in the human genome will provide a means of predicting risk of a variety of complex diseases. Single nucleotide polymorphisms (SNPs) axe the most common form of genomic variation. Haplotypes have been suggested as one means for reducing the complexity of studying SNPs. In this paper we review some of the computational approaches that have been. taking for determining haplotypes and suggest new approaches.
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页码:26 / 47
页数:22
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