A diagnostic challenge: Cystic carcinoma of the thyroid with squamous and papillary differentiation

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作者
Rausch, Th. [1 ]
Sutter, M. [2 ]
Andrejevic-Blant, S. [1 ]
机构
[1] Univ Lausanne, Fac Med & Biol, CHUV Hosp, Inst Pathol, CH-1011 Lausanne, Switzerland
[2] Univ Lausanne, Fac Med & Biol, CHUV Hosp, Dept Visceral Surg, CH-1011 Lausanne, Switzerland
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R36 [病理学];
学科分类号
100104 ;
摘要
The well-differentiated papillary thyroid carcinoma associated with poorly differentiated squamous cell carcinoma denotes rare tumors of the thyroid displaying dual, morphological and immunophenotypical features of both components within the same lesion and presents highly difficult task for both, surgeon and pathologist. We present a case of a 82-year old female with a painless left latero-cervical swelling, increased in size over the last 6-months, compressing trachea, extending to larynx, hypopharynx and filing in the left thyroid lobe. The histopathological examination yielded two intermingled morphologically different patterns including conventional papillary thyroid carcinoma and poorly differentiated squamous cell carcinoma with cystic features. This particular presentation of thyroid carcinoma carries a poor prognosis with high recurrence rate and metastases over distant sites in about 20% of the cases. Key words: Thyroid, papillary carcinoma, squamous cell carcinoma.
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页码:27 / +
页数:3
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