Evaluation of combined anti-PD-1 immunotherapy and radiation therapy in a preclinical mouse model of pneumonitis and fibrosis

被引：6
|
作者：
Nichols, Derek [1 ]
Boyle, Theresa A. [2 ]
Noyes, David [1 ]
Latin, Kujtim [3 ]
Feygelman, Vladimir [3 ]
Jackson, Isabel [4 ]
Vujaskovic, Zeljko [4 ]
Antonia, Scott [1 ,5 ]
Perez, Bradford A. [1 ,2 ,3 ,5 ]
机构：
[1] H Lee Moffitt Canc Ctr & Res Inst, Dept Immunol, Tampa, FL 33612 USA
[2] H Lee Moffitt Canc Ctr & Res Inst, Dept Pathol, Tampa, FL 33612 USA
[3] H Lee Moffitt Canc Ctr & Res Inst, Dept Radiat Oncol, Tampa, FL 33612 USA
[4] Univ Maryland, Div Translat Radiat Sci, Dept Radiat Oncol, Sch Med, Baltimore, MD 21202 USA
[5] H Lee Moffitt Canc Ctr & Res Inst, Dept Thorac Oncol, Tampa, FL 33612 USA
来源：
JOURNAL OF THORACIC DISEASE | 2018年 / 10卷 / 11期
关键词：
CELL LUNG-CANCER; NIVOLUMAB; SAFETY; PEMBROLIZUMAB; CHEMORADIATION; RADIOTHERAPY; CARBOPLATIN; IRRADIATION; IPILIMUMAB; CONCURRENT;
D O I：
10.21037/jtd.2018.10.01
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
[No abstract available]
引用
收藏
页码：6254 / +
页数：8
相关论文
共 50 条
  • [1] Pneumonitis with anti-PD-1/PD-L1 therapy
    Naidoo, J.
    Cunningham, J.
    Woo, K. M.
    Hellmann, M. D.
    Postow, M. A.
    Drilon, A. E.
    Chaft, J. E.
    Lesokhin, A. M.
    Segal, N. H.
    Callahan, M. K.
    Rudin, C. M.
    Iyriboz, T.
    Wolchok, J. D.
    EUROPEAN JOURNAL OF CANCER, 2015, 51 : S103 - S103
  • [2] Pneumonitis From Anti-PD-1/PD-L1 Therapy
    Balaji, Aanika
    Verde, Franco
    Suresh, Karthik
    Naidoo, Jarushka
    ONCOLOGY-NEW YORK, 2017, 31 (10): : 739 - +
  • [3] Computational model of combined cancer treatment with radiotherapy and anti-PD-1 immunotherapy
    Valentinuzzi, Damijan
    Ursic, Katja
    Vrankar, Martina
    Simoncic, Urban
    Simoncic, Urban
    Jeraj, Robert
    CANCER IMMUNOLOGY RESEARCH, 2017, 5 (03)
  • [4] Immunotherapy Macrophages hijack anti-PD-1 therapy
    Killock, David
    NATURE REVIEWS CLINICAL ONCOLOGY, 2017, 14 (07) : 394 - 394
  • [5] Analysis of Immune Correlates Using Anti-PD-1 Checkpoint Blockade Immunotherapy Combined With Stereotactic Body Radiation Therapy
    Kim, S.
    Sanders, P. D.
    Weihe, E.
    Purcell, T.
    Kato, S.
    Patel, S.
    Kurzrock, R.
    Sharabi, A.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2017, 99 (02): : E602 - E603
  • [6] COMBINING ANTI-PD-1 IMMUNOTHERAPY WITH STEREOTACTIC RADIOSURGERY IN A MOUSE ORTHOTOPIC GLIOBLASTOMA MODEL
    Zeng, J.
    See, A.
    Phallen, J.
    Belcaid, Z.
    Durham, N.
    Meyer, C.
    Pradilla, G.
    Ford, E.
    Wong, J.
    Hammers, H.
    Tyler, B.
    Brem, H.
    Tran, P.
    Pardoll, D.
    Lim, M.
    RADIOTHERAPY AND ONCOLOGY, 2012, 102 : S34 - S34
  • [7] Local therapy combined with anti-PD-1 immunotherapy for advanced lung adenocarcinoma: A case report
    Wu, Na
    Yang, Xiaoxin
    Zhai, Yan
    Lu, Wei
    JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2024, 20 (02) : 739 - 744
  • [8] Preclinical development and clinical studies of targeted JAK/STAT combined Anti-PD-1/PD-L1 therapy
    Chen, Miaomiao
    Wang, Siliang
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 130
  • [9] Prognostic significance of the radiologic features of pneumonitis induced by anti-PD-1 therapy
    Watanabe, Satoshi
    Ota, Takeshi
    Hayashi, Masachika
    Ishikawa, Hiroyuki
    Otsubo, Aya
    Shoji, Satoshi
    Nozaki, Koichiro
    Ichikawa, Kosuke
    Kondo, Rie
    Miyabayashi, Takao
    Miura, Satoru
    Tanaka, Hiroshi
    Abe, Tetsuya
    Okajima, Masaaki
    Terada, Masaki
    Ishida, Takashi
    Iwashima, Akira
    Sato, Kazuhiro
    Yoshizawa, Hirohisa
    Kikuchi, Toshiaki
    CANCER MEDICINE, 2020, 9 (09): : 3070 - 3077
  • [10] EFFECT OF COMBINED ANTI-PD-1 AND TEMOZOLOMIDE THERAPY IN GLIOBLASTOMA
    Park, Junseong
    Kim, Chang Gon
    Lee, Jae Eun
    Shim, Jin-Kyoung
    Kim, Eui Hyun
    Chang, Jong Hee
    Shin, Eui-Cheol
    Kang, Seok-Gu
    NEURO-ONCOLOGY, 2018, 20 : 123 - 124
12345