Long-Term Follow-Up of Men Invited to Participate in a Population-Based Abdominal Aortic Aneurysm Screening Program

被引:14
|
作者
Hultgren, Rebecka [1 ,2 ]
Elfstrom, K. Miriam [3 ]
Ohman, Daniel [3 ]
Linne, Anneli [4 ,5 ]
机构
[1] Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden
[2] Karolinska Univ Hosp, Dept Vasc Surg, Stockholm, Sweden
[3] Reg Canc Ctr Stockholm Gotland, Stockholm, Sweden
[4] Karolinska Inst, Dept Clin Sci & Educ, Sodersjukhuset, Stockholm, Sweden
[5] Soder Sjukhuset, Sect Vasc Surg, Dept Surg, Sjukhusbacken 10, S-11861 Stockholm, Sweden
关键词
screening; aneurysm; abdominal aortic aneurysm; natural history; treatment; outcome; attendance; prevalence; SURFACE-AREA; RISK-FACTORS; RUPTURE; DIAMETER; VOLUME; SURGERY; GROWTH;
D O I
10.1177/0003319720921741
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
A screening program for abdominal aortic aneurysm (AAA), inviting 65-year-old men, was started in Stockholm in 2010 (2.3 million inhabitants). The aim was to present a long-term follow-up of men participating in screening, as well as AAA repair and ruptures among nonparticipants. Demographics were collected for men with screening detected with AAA 2010 to 2016 (n = 672) and a control group with normal aortas at screening (controls, n = 237). Medical charts and regional Swedvasc (Swedish Vascular registry) data were analyzed for aortic repair for men born 1945 to 1951. Ultrasound maximum aortic diameter (AD) as well as Aortic Size Index (ASI) was recorded. Participation was 78% and prevalence of AAA was 1.2% (n = 672). Aortic repair rates correlated with high ASI and AD. During the study period, 22% of the AAA patients were treated with the elective repair; 35 men in surveillance died (5.2%), non-AAA-related causes (82.9%) dominated, followed by unknown causes among 4 (11.4%), and 2 (5.7%) possibly AAA-related deaths. Abdominal aortic aneurysm rupture rate was higher among nonparticipants (0.096% vs 0.0036%, P < .001). The low dropout rate confirms acceptability of follow-up after screening. The efficacy is shown by the much higher rupture rate among the nonparticipating men.
引用
收藏
页码:641 / 649
页数:9
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