Successful management of adult respiratory distress syndrome (ARDS) after high-dose chemotherapy and peripheral blood progenitor cell rescue by non-invasive ventilatory support

被引:19
|
作者
Rabitsch, W
Staudinger, T
Brugger, SA
Reiter, E
Keil, F
Herold, C
Lechner, K
Greinix, HT
Kalhs, P
机构
[1] Univ Vienna, Dept Internal Med 1, Bone Marrow Transplantat Unit, A-1090 Vienna, Austria
[2] Univ Vienna, Dept Internal Med 1, Intens Care Unit, A-1090 Vienna, Austria
[3] Univ Vienna, Dept Radiol, A-1090 Vienna, Austria
[4] Univ Vienna, Dept Internal Med 1, Hematol Unit, A-1090 Vienna, Austria
关键词
high-dose chemotherapy and peripheral blood progenitor cell rescue non-invasive ventilatory support; non-invasive ventilation; CPAP; ARDS;
D O I
10.1038/sj.bmt.1701215
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A 34-year-old man suffering from Hodgkin's disease underwent high-dose chemotherapy (CBV) followed by transplantation of autologous peripheral blood stem cells. On day +6 after peripheral blood stem cell transplant (PBSCT) bacterial pneumonia developed. Along with rapid engraftment during stimulation with G-CSF adult respiratory distress syndrome (ARDS) developed within 4 days, High-flow CPAP (continuous positive airway pressure) ventilation via a sealed face-mask was initiated. The patient tolerated the sealed face-mask very well, and CPAP was continuously administered for 4 days, thus avoiding intubation, High-flow CPAP may offer a therapeutic alternative in selected patients with respiratory compromise after PBSCT.
引用
收藏
页码:1067 / 1069
页数:3
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