The role of ABO-incompatible living donors in kidney transplantation: State of the art

被引：8
|
作者：
Thielke, James
Kaplan, Bruce
Benedetti, Enrico
机构：
[1] Univ Illinois, Dept Pharm, Chicago, IL 60680 USA
[2] Univ Illinois, UIC Multiorgan Transplant Inst, Chicago, IL 60680 USA
[3] Univ Illinois, Dept Surg, Div Transplantat, Chicago, IL 60680 USA
来源：
SEMINARS IN NEPHROLOGY | 2007年 / 27卷 / 04期
关键词：
ABO incompatibility; hyperacute rejection; living donor kidney transplantation;
D O I：
10.1016/j.semnephrol.2007.03.003
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Summary: In the past, ABO incompatibility has been considered an absolute contraindication for living donor kidney transplantation. Over the past 25 years, advances in immunosuppressive therapy and progressively more refined desensitization protocols have allowed increasingly successful transplantations across the ABO barrier. Current results of kidney transplants from ABO-incompatible living donors are quite favorable and comparable in the long term with the outcome of ABO-compatible organs both in Japan and in the United States. The present article reviews the history, outcomes, and current issues in kidney transplantation with ABO-incompatible living donors in adult and pediatric recipients. © 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码：408 / 413
页数：6
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