The influence of porous structure on the corrosion behavior and biocompatibility of bulk Ti-based metallic glass

To mimic the biomechanical properties of natural bone, the porous Ti45Zr10Cu31Pd10Sn4 bulk metallic glass (BMG) with bone-like mechanical characteristics was developed by one step SPS method. In this work, the introduced pore contributions to the corrosion behavior in simulated body fluid and the biocompatibility of BMG were further explored. According to the findings, the porous BMG not only outperforms commercial Ti-based orthopedic implants (CP-Ti and Ti-6Al-4V) in terms of corrosion resistance, but also ranks among the porous biomedical alloys that have been reported. Simultaneously, in vitro investigations revealed that MC3T3 cells co-cultured with porous BMGs could multiply normally, indicating the porous BMG's remarkable biocompatibility.(C) 2022 Elsevier B.V. All rights reserved.