Synthesis of a CDE fragment of the insect antifeedant 12-hydroxyazadiradione

被引：28
|
作者：
FernandezMateos, A
Coca, GP
Gonzalez, RR
Hernandez, CT
机构：
[1] Universidad de Salamanca, Facultad de C. Químicas, Depto. de Quim. Orgánica, 37008 Salamanca
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1996年 / 61卷 / 26期
关键词：
D O I：
10.1021/jo961100j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A diastereoselective and versatile synthesis of the model insect antifeedant 23 related to 12-hydroxyazadiradione has been achieved in 11 steps starting from alpha-cyclocitral, 1. The key steps involve intramolecular 1,3-dipolar cycloaddition of a nitrile oxide and a Stille coupling reaction of a vinyl iodide with a stannylfuran.
引用
收藏
页码：9097 / 9102
页数：6
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