Does heterogeneity in measured calibrated thrombin generation assay or FVIII activity (<1%) explain clinical heterogeneity in severe hemophilia A?

被引：0

作者：

Sinclair, G. D. ^{[1
,2
]}

Blanchette, V ^{[3
]}

Card, R. T. ^{[4
]}

Chan, A. K. C. ^{[5
]}

Israels, S. ^{[6
]}

Lillicrap, D. ^{[7
]}

Rivard, G. ^{[8
]}

Robinson, S. ^{[9
]}

Vickars, L. ^{[10
]}

Williams, Z. ^{[11
]}

Wu, J. K. M. ^{[12
]}

Poon, M. ^{[13
]}

机构：

[1] Univ Calgary, Pathol & Lab Med, Calgary, AB, Canada

[2] Calgary Lab Serv, Calgary, AB, Canada

[3] Hosp Sick Children, Pediat, Toronto, ON, Canada

[4] Royal Univ Hosp, Med, Saskatoon, SK, Canada

[5] McMaster Univ, Pediat, Hamilton, ON, Canada

[6] CancerCare Manitoba, Pediat, Winnipeg, MB, Canada

[7] Queens Univ, Pathol & Mol Med, Kingston, ON, Canada

[8] Hop Ste Justine, Pediat, Montreal, PQ, Canada

[9] QEII Hlth Sci Ctr, Med, Halifax, NS, Canada

[10] St Pauls Hosp, Med, Vancouver, BC, Canada

[11] Univ Calgary, Med, Calgary, AB, Canada

[12] BC Childrens Hosp, Pediat, Vancouver, BC, Canada

[13] Univ Calgary, Med Pediat & Oncol, Calgary, AB, Canada

来源：

JOURNAL OF THROMBOSIS AND HAEMOSTASIS | 2009年 / 7卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OC-TU-068

引用

页码：189 / 189

页数：1

共 6 条

[1] Investigation of the phenotype heterogeneity in severe hemophilia A using thromboelastography, thrombin generation, and thrombodynamics
Tarandovskiy, Ivan D.
Balandina, Anna N.
Kopylov, Konstantine G.
Konyashina, Nadezhda I.
Kumskova, Maria A.
Panteleev, Mikhail A.
Ataullakhanov, Fazoil I.
THROMBOSIS RESEARCH, 2013, 131 (06) : E274 - E280
[2] Thrombin generation assay by calibrated automated thrombogram (CAT): application to monitoring severe hemophilia A treatment
Vila, V.
Moret, A.
Cabrera, N.
Espana, F.
Martinez-Sales, V
Aznar, J. A.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2013, 11 : 537 - 537
[3] Multicenter Evaluation of the Hemostatic Activity of Emicizumab in Patients with Severe Hemophilia a Using Thrombin Generation Assay
Josset, Laurie
Janbain, Maissaa
De Wreede, Annaelle
Nougier, Christophe
Desage, Stephanie
Lienhart, Anne
Delavenne, Xavier
Dargaud, Yesim G.
BLOOD, 2023, 142
[4] Variation in blood clotting and thrombin generation among boys with severe hemophilia A tested at FVIII levels less than 1%
Kahr, W.
Pluthero, F.
Stain, A.
Hilliard, P.
Blanchette, C.
Hang, M.
Blanchette, V.
HAEMOPHILIA, 2008, 14 : 25 - 25
[5] Correlation of peak thrombin concentrations with one-stage activity assay levels indicates that thrombin generation assays correlate with factor VIII activity in clinical hemophilia A plasma samples
Patel-Hett, S.
Lee, J.
Rakhe, S.
Arkin, S.
Huard, F.
Pittman, D. D.
Murphy, J. E.
Hua, F.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2015, 13 : 794 - 795
[6] Impact of corn trypsin inhibitor (CTI) on the thrombin generation assay of plasma samples collected from a phase 3 multicenter clinical trial in severe hemophilia A subjects
Buyue, Y.
Jiang, H.
Brennan, A.
Sommer, J. M.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2014, 12 : 41 - 41

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