An L433P Arrhythmia-linked Mutation In RyR2 Uncouples Agonist-evoked Ca2+ Release From Homeostatic Ca2+ Cycling

被引：0
|
作者：
Clack, Aaron I. [1 ]
Fry, Debra L. [1 ]
Thomas, N. Lowri [1 ]
Lai, F. Anthony [1 ]
George, Christopher H. [1 ]
机构：
[1] Cardiff Univ, Wales Heart Res Inst, Cardiff, S Glam, Wales
来源：
BIOPHYSICAL JOURNAL | 2009年 / 96卷 / 03期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
571-Pos
引用
收藏
页码：111A / 111A
页数：1
相关论文
共 50 条
  • [1] Differential impacts of arrhythmia-linked loss-of-function RyR2 mutations on Ca2+ signaling in cardiac cells
    Kurebayashi, Nagomi
    Murayama, Takashi
    Tetsuo, Naoyuki
    Hirose, Sayako
    Horie, Minoru
    Ohno, Seiko
    Sakurai, Takashi
    BIOPHYSICAL JOURNAL, 2022, 121 (03) : 175A - 175A
  • [2] Agonist-Evoked Ca2+ Wave Progression Requires Ca2+ and IP3
    McCarron, John G.
    Chalmers, Susan
    MacMillan, Debbi
    Olson, Marnie L.
    JOURNAL OF CELLULAR PHYSIOLOGY, 2010, 224 (02) : 334 - 344
  • [3] FEEDBACK INHIBITION OF CA2+ RELEASE BY CA2+ IS THE UNDERLYING MECHANISM OF AGONIST-EVOKED INTRACELLULAR CA2+ OSCILLATIONS IN PANCREATIC ACINAR-CELLS
    ZHANG, BX
    MUALLEM, S
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1992, 267 (34) : 24387 - 24393
  • [4] Characterization of Ca2+ - Induced Ca2+ Release via RyR2 Carrying Arrhythmogenic Mutations
    Kurebayashi, Nagomi
    Murayama, Takashi
    Suzuki, Junji
    Kanemaru, Kazunori
    Iino, Masamitsu
    Sakurai, Takashi
    BIOPHYSICAL JOURNAL, 2016, 110 (03) : 268A - 268A
  • [5] Agonist-evoked endothelial Ca2+ signalling microdomains
    Murphy, Timothy V.
    Sandow, Shaun L.
    CURRENT OPINION IN PHARMACOLOGY, 2019, 45 : 8 - 15
  • [6] THE PATTERN OF AGONIST-EVOKED CYTOSOLIC CA2+ OSCILLATIONS DEPENDS ON THE RESTING INTRACELLULAR CA2+ CONCENTRATION
    TOESCU, EC
    LAWRIE, AM
    GALLACHER, DV
    PETERSEN, OH
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1993, 268 (25) : 18654 - 18658
  • [7] Elucidation of Mechanism of Ca2+ Induced Ca2+ Release of Ryr2 Revealed by Cryo-EM
    Kobayashi, Takuya
    Tsutsumi, Akihisa
    Kurebayashi, Nagomi
    Saito, Kei
    Sakurai, Takashi
    Kikkawa, Masahide
    Murayama, Takashi
    Ogawa, Haruo
    BIOPHYSICAL JOURNAL, 2020, 118 (03) : 34A - 34A
  • [8] Inactivation of Ca2+ Release Channels (Ryanodine Receptors RyR1 and RyR2) with Rapid Steps in [Ca2+] and Voltage
    Laver, D. R.
    Lamb, G. D.
    Biophysical Journal, 74 (05):
  • [9] Inactivation of Ca2+ release channels (ryanodine receptors RyR1 and RyR2) with rapid steps in [Ca2+] and voltage
    Laver, DR
    Lamb, GD
    BIOPHYSICAL JOURNAL, 1998, 74 (05) : 2352 - 2364
  • [10] RyR2 Serine-2030 PKA Site Governs Ca2+ Release Termination and Ca2+ Alternans
    Wei, Jinhong
    Guo, Wenting
    Wang, Ruiwu
    Estillore, John Paul
    Belke, Darrell
    Chen, Yong-Xiang
    Vallmitjana, Alexander
    Benitez, Raul
    Hove-Madsen, Leif
    Chen, S. R. Wayne
    CIRCULATION RESEARCH, 2023, 132 (02) : e59 - e77
12345