1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis

被引:3
|
作者
Ribeiro, Ruan Carlos B. [1 ]
Ferreira, Patricia G. [2 ]
Borges, Amanda de A. [1 ]
Forezi, Luana da S. M. [1 ]
da Silva, Fernando de Carvalho [1 ]
Ferreira, Vitor F. [2 ]
机构
[1] Univ Fed Fluminense, Inst Quim, Dept Quim Organ, Campus Valonguinho, BR-24020150 Niteroi, RJ, Brazil
[2] Univ Fed Fluminense, Dept Tecnol Farmaceut, Fac Farm, BR-24241000 Niteroi, RJ, Brazil
来源
关键词
biological activities; derivatization reagents; beta-NQS; organic synthesis; SOLID-STATE FLUORESCENCE; SPECTROPHOTOMETRIC DETERMINATION; THEILERIA-ANNULATA; HETEROCYCLIC-DERIVATIVES; TRYPANOCIDAL ACTIVITY; URINE SAMPLES; IN-VIVO; NAPHTHOQUINONES; SODIUM; TAUTOMERISM;
D O I
10.3762/bjoc.18.5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Several low molecular weight naphthoquinones are very useful in organic synthesis. These compounds have given rise to thousands of other naphthoquinones that have been tested against various microorganisms and pharmacological targets, including being used in the preparation of several drugs that are on the pharmaceutical market. Among these naphthoquinones, the series of compounds prepared from 1,2-naphthoquinone-4-sulfonic acid salts (beta-NQS) stands out. In addition to being used in organic synthesis, they are excellent analytical derivatization reagents to spectrophotometrically determine drugs containing primary and secondary amino groups. This review summarizes the literature involving beta-NQS.
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页码:53 / 69
页数:17
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