Cu-Catalyzed Tandem Oxidation of N-Substituted Indolines to Isatins

被引：2

作者：

Gao, Shanshan ^{[1
]}

Zheng, Junliang ^{[1
]}

Ge, Guoping ^{[1
]}

Luo, Junfei ^{[1
]}

机构：

[1] Ningbo Univ, Sch Mat Sci & Chem Engn, Ningbo 315211, Zhejiang, Peoples R China

来源：

CHEMISTRYSELECT | 2018年 / 3卷 / 46期

关键词：

Cu-catalyzed; N-substituted indolines; Isatin derivatives; Oxidation; tert-Butyl hydroperoxide; ANTICANCER ACTIVITY; GENERAL-METHOD; INDOLES; DESIGN; FUNCTIONALIZATION; DEHYDROGENATION; AROMATIZATION; CONVENIENT; INHIBITORS; ALKALOIDS;

D O I：

10.1002/slct.201803312

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The direct transformation of N-substituted indoline to isatin derivatives has been developed, this reaction employed cheap Cu catalyst and aqueous tert-butyl hydroperoxide as an oxidant. Primary mechanism studies suggested that the indolines was initially oxidized to indoles which further undergo Cu-catalyzed oxidation to isatins.

引用

页码：13178 / 13181

页数：4

共 50 条

[1] Cu-catalyzed oxidation of indoles to isatins
Luo, Junfei
Zhao, Yanchao
Xu, Xing
Zheng, Junliang
Liang, Hongze
TETRAHEDRON LETTERS, 2017, 58 (49) : 4591 - 4594
[2] Cu-Catalyzed Intramolecular Amidation of Unactivated C(sp3)-H Bonds To Synthesize N-Substituted Indolines
Pan, Fei
Wu, Bin
Shi, Zhang-Jie
CHEMISTRY-A EUROPEAN JOURNAL, 2016, 22 (19) : 6487 - 6490
[3] Kinetics of N-substituted phenothiazines and N-substituted phenoxazines oxidation catalyzed by fungal laccases
Tetianec, Lidija
Kulys, Juozas
CENTRAL EUROPEAN JOURNAL OF BIOLOGY, 2009, 4 (01): : 62 - 67
[4] Iodine-Catalyzed Oxidation of N-Substituted Indoles by using Chloramine-B: A Facile and Practical Approach to Isatins
Liu, Peijun
Guo, Jiajing
Wei, Wentao
Liu, Xiaozu
Sun, Pinghua
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 2016 (12) : 2105 - 2109
[5] Highly efficient quinone-catalyzed aerobic dehydrogenation of N-substituted indolines to indoles
Li, Bao
Stahl, Shannon
Wendlandt, Alison
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
[6] Oxoammonium-Catalyzed Oxidation of N-Substituted Amines
Rein, Jonas
Górski, Bartosz
Cheng, Yukun
Lei, Zhen
Buono, Frederic
Lin, Song
Journal of the American Chemical Society, 2024, 146 (46) : 31412 - 31419
[7] L-proline-catalyzed asymmetric aldol condensation of N-substituted isatins with acetone
Chen, Gang
Wang, Ye
He, Hongping
Gao, Suo
Yang, Xiaosheng
Hao, Xiaojiang
HETEROCYCLES, 2006, 68 (11) : 2327 - 2333
[8] Enantioselective N-propargylation of indoles via Cu-catalyzed propargylic alkylation/dehydrogenation of indolines
Zhu, Fulin
Hu, Xiangping
CHINESE JOURNAL OF CATALYSIS, 2015, 36 (01) : 86 - 92
[9] NEW N-SUBSTITUTED ISATINS AND DERIVATIVES WITH PHARMACOLOGICAL ACTIVITY
SAINTRUF, G
BOURGEAD.JC
CHIMICA THERAPEUTICA, 1973, 8 (04): : 447 - 450
[10] N-SUBSTITUTED ISATINS FROM PHENYLNITRONES OF GLYOXYL ANILIDES
HEINISCH, L
JOURNAL FUR PRAKTISCHE CHEMIE, 1975, 317 (03): : 435 - 447

← 1 2 3 4 5 →