CFD modeling of airborne pathogen transmission of COVID-19 in confined spaces under different ventilation strategies

Airborne transmission is an important route of spread of viral diseases (e.g., COVID-19) inside the confined spaces. In this respect, computational fluid dynamics (CFD) emerged as a reliable and fast tool to understand the complex flow patterns in such spaces. Most of the recent studies, nonetheless, focused on the spatial distribution of airborne pathogens to identify the infection probability without considering the exposure time. This research proposes a framework to evaluate the infection probability related to both spatial and temporal parameters. A validated Eulerian-Lagrangian CFD model of exhaled droplets is first developed and then evalu-ated with an office case study impacted by different ventilation strategies (i.e., cross-(CV), single-(SV), me- chanical-(MV) and no-ventilation (NV)). CFD results were analyzed in a bespoke code to calculate the tempo -spatial distribution of accumulated airborne pathogens. Furthermore, two indices of local and general infec-tion risks were used to evaluate the infection probability of the ventilation scenarios. The results suggest that SV has the highest infection probability while SV and NO result in higher dispersions of airborne pathogens inside the room. Eventually, the time history of indices reveals that the efficiency of CV and MV can be poor in certain regions of the room.