A new HLA-Cw allele (Cw*1510), identified in a French Caucasian individual

被引：0
|
作者：
Tamouza, R
Schaeffer, V
Marzais, F
Poirier, JC
Fortier, C
Ramasawmy, R
Sghiri, R
Krishnamoorthy, R
Toubert, A
Charron, D
机构：
[1] Univ Paris 07, IUH,Hop St Louis, AP HP, Lab Immunol & Histocompatibil, F-75010 Paris, France
[2] INSERM U396, Paris, France
[3] Hop Robert Debre, INSERM U458, F-75019 Paris, France
来源：
TISSUE ANTIGENS | 2001年 / 58卷 / 02期
关键词：
HLA-Cw*1510; gene conversion; French Caucasian individual;
D O I：
10.1034/j.1399-0039.2001.580209.x
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
A novel HLA-Cw*15 allele, Cw*1510, found in a French Caucasian bone marrow recipient is described. Nucleotide sequence of the new variant is identical to the common Cw*15021 DNA sequences except nucleotides at positions 32 and 61 of exon 2. While the first difference is silent, the second cause substitution of an Histidine by an Arginine at amino acid position 21 of the alpha1 heavy chain domain.
引用
收藏
页码：107 / 108
页数：2
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