Explorations of [4+2] and [5+2] Cycloadditions of Dienylcyclopropane Derived Enzymatically from Cyclopropylbenzene

被引：5
|
作者：
Hudlicky, Jason Reed
Hopkins-Hill, John
Hudlicky, Tomas [1 ]
机构：
[1] Brock Univ, Dept Chem, St Catharines, ON L2S 3A1, Canada
来源：
SYNLETT | 2011年 / 19期
基金：
加拿大自然科学与工程研究理事会; 加拿大创新基金会;
关键词：
dienylcyclopropane; cyclopropylbenzene; 4+2] cycloadditions; 5+2] cycloadditions; enzymatic dihydroxylation of arenes; DIELS-ALDER REACTION; MICROBIAL OXIDATION; ENANTIOSELECTIVE SYNTHESIS; CHEMOENZYMATIC SYNTHESIS; ABSOLUTE-CONFIGURATION; OSELTAMIVIR TAMIFLU; AROMATIC-COMPOUNDS; AMINO CYCLITOLS; VINYLCYCLOPROPANES; DIHYDROXYLATION;
D O I：
10.1055/s-0031-1289553
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Fermentation of cyclopropylbenzene with E. coli JM109(pDTG601a) furnished optically pure 1-cyclopropyl-2,3-dihydroxycyclohexa-4,6-diene whose reactivity in [4+2]- and [5+2]-cycloaddition chemistry was explored.
引用
收藏
页码：2891 / 2895
页数：5
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