Fulminant ulcerative colitis despite maximal immunosuppression following liver transplantation: A case report and literature review

被引：6
|
作者：
Pan, Antony [1 ]
Schlup, Martin [1 ,2 ]
Lubcke, Ralf [1 ]
Schultz, Michael [1 ,2 ]
机构：
[1] So Dist Hlth Board, Gastroenterol Unit, Dunedin, New Zealand
[2] Univ Otago, Dunedin Sch Med, Med Sect, Dept Med & Surg Sci, Dunedin 9054, New Zealand
来源：
JOURNAL OF CROHNS & COLITIS | 2011年 / 5卷 / 05期
关键词：
Ulcerative colitis; Primary sclerosing cholangitis; Liver transplantation; Immunosuppression; Colitis; INFLAMMATORY-BOWEL-DISEASE; MYCOPHENOLATE-MOFETIL; MANAGEMENT; RECIPIENTS; EFFICACY; THERAPY;
D O I：
10.1016/j.crohns.2011.04.011
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Inflammatory Bowel Disease (IBD) is thought to be the result of an overly aggressive immune response to ubiquitous antigens. Immuno -modulation and -suppression is therefore currently the treatment of choice. It was long anticipated that the course of pre-existing IBD should improve after orthotopic liver transplantation (OLT) due to increased immunosuppression. We report the case of a patient who developed acute fulminant colitis despite triple immunosuppression and mesalazine and review the relevant literature. (C) 2011 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：465 / 468
页数：4
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