Radiotherapy and Immunotherapy Combinations in Non-small Cell Lung Cancer: A Promising Future?

被引：8

作者：

Hanna, G. G. ^{[1
]}

Illidge, T. ^{[2
]}

机构：

[1] Queens Univ Belfast, Ctr Canc Res & Cell Biol, 95 Lisburn Rd, Belfast BT9 7AE, Antrim, North Ireland

[2] Univ Manchester, Manchester Acad Hlth Sci Ctr, Inst Canc Sci, Manchester Canc Res Ctr,Christie Hosp, Manchester, Lancs, England

来源：

CLINICAL ONCOLOGY | 2016年 / 28卷 / 11期

关键词：

Checkpoint inhibition; immunotherapy; NSCLC; radiotherapy; IMMUNE-RELATED RESPONSE; TUMOR MICROENVIRONMENT; IONIZING-RADIATION; SOLID TUMORS; MELANOMA; MODULATION; MECHANISMS; IPILIMUMAB; RESISTANCE; DOCETAXEL;

D O I：

10.1016/j.clon.2016.07.014

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The goal of re-programming the host immune system to target malignancy with durable anti-tumour clinical responses has been speculated for decades. In the last decade such speculation has been transformed into reality with unprecedented and durable responses to immune checkpoint inhibitors seen in solid tumours. This mini-review considers the mechanism of action of immune modulating agents and the potential for combination with radiotherapy in the treatment of non-small cell lung cancer. (C) 2016 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

引用

页码：726 / 731

页数：6

共 50 条

[1] Toxicity with small molecule and immunotherapy combinations in non-small cell lung cancer
Adderley, H.
Blackhall, F. H.
Lindsay, C. R.
CANCER IMMUNOLOGY IMMUNOTHERAPY, 2021, 70 (03) : 589 - 595
[2] Toxicity with small molecule and immunotherapy combinations in non-small cell lung cancer
H. Adderley
F. H. Blackhall
C. R. Lindsay
Cancer Immunology, Immunotherapy, 2021, 70 : 589 - 595
[3] Immunotherapy-chemotherapy combinations for non-small cell lung cancer: current trends and future perspectives
Cella, Eugenia
Zullo, Lodovica
Marconi, Silvia
Rossi, Giovanni
Coco, Simona
Dellepiane, Chiara
Alama, Angela
Rozeboom, Leslie
Bennicelli, Elisa
Parisi, Francesca
Sacco, Gianluca
Barletta, Giulia
Zinoli, Linda
Tagliamento, Marco
Pronzato, Paolo
Genova, Carlo
EXPERT OPINION ON BIOLOGICAL THERAPY, 2022, 22 (10) : 1259 - 1273
[4] The Integration of Radiotherapy with Immunotherapy for the Treatment of Non-Small Cell Lung Cancer
Ko, Eric C.
Raben, David
Formenti, Silvia C.
CLINICAL CANCER RESEARCH, 2018, 24 (23) : 5792 - 5806
[5] Immunotherapy in non-small cell lung cancer: The past, the present, and the future
Lu, Meng
Su, Yanjun
THORACIC CANCER, 2019, 10 (04) : 585 - 586
[6] New challenges in the combination of radiotherapy and immunotherapy in non-small cell lung cancer
Luna, Javier
Zafra, Juan
Areses Manrique, Ma Carmen
Rodriguez, Aurora
Sotoca, Amalia
Firvida, Jose Luis
Chicas-Sett, Rodolfo
Mielgo, Xabier
Reyes, Juan Carlos Trujillo
Counago, Felipe
WORLD JOURNAL OF CLINICAL ONCOLOGY, 2021, 12 (11): : 983 - 999
[7] Prior or concurrent radiotherapy and nivolumab immunotherapy in non-small cell lung cancer
Ratnayake, G.
Shankar, M.
Roberts, K.
Mason, R.
Hughes, B. G. M.
Lwin, Z.
Jain, V.
O'Byrne, K. J.
Chua, B.
ANNALS OF ONCOLOGY, 2018, 29 : 533 - 533
[8] Combination Immunotherapy With Radiotherapy in Non-Small Cell Lung Cancer: A Review of Evidence
Burr, Justin L.
Johnson, Kurtis C.
Carmicheal, Joseph J.
Lin, Chi
Ganti, Apar Kishor
CANCER MEDICINE, 2024, 13 (21):
[9] Prior or concurrent radiotherapy and nivolumab immunotherapy in non-small cell lung cancer
Ratnayake, Gishan
Shanker, Mihir
Roberts, Kate
Mason, Robert
Hughes, Brett G. M.
Lwin, Zarnie
Jain, Vikram
O'Byrne, Kenneth
Lehman, Margot
Chua, Benjamin
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2020, 16 (01) : 56 - 62
[10] Immunotherapy for Non-Small Cell Lung Cancer
Yoon, Sung Ho
TUBERCULOSIS AND RESPIRATORY DISEASES, 2014, 77 (03) : 111 - 115

← 1 2 3 4 5 →