Leptospirosis: a diagnostic conundrum

被引:1
|
作者
Gurumurthy, Keerthivasan [1 ]
Narasimha, Harish Belgode [2 ]
Wyawahare, Mukta [3 ]
Biswal, Niranjan [4 ]
机构
[1] Amrita Vishwa Vidyapeetham, Dept Microbiol, Kochi 682041, Kerala, India
[2] Jawaharlal Inst Postgrad Med Educ & Res, Dept Microbiol, Pondicherry, India
[3] Jawaharlal Inst Postgrad Med Educ & Res, Dept Gen Med, Pondicherry, India
[4] Jawaharlal Inst Postgrad Med Educ & Res, Dept Paediat, Pondicherry, India
关键词
Asia; bacterial infection; community health; Leptospirosis; PCR; epidemiology; TESTS; ASSAY;
D O I
10.1177/0049475518788470
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Leptospirosis is a serious public health concern worldwide. It is highly endemic in the Andaman Islands and its prevalence is increasing in other Indian states. Clinical features are non-specific and diagnosis relies on laboratory confirmation. The gold standard is microscopic agglutination testing, but this is not widely available. Real-time polymerase chain reaction testing of LipL32 antigen provides the earliest detection of pathogenic Leptospira in the body. We found it to be 100% specific, but it should be used in the first 10 days of illness for reliable results.
引用
收藏
页码:306 / 309
页数:4
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