A long-lasting, complete hematologic and cytogenetic remission of chronic myelogenous leukemia after treatment with busulfan alone

被引：2
|
作者：
Mandigers, CMPW
Mensink, EJBM
van Kessel, AG
van der Plas, DC
Haanen, C
Hagemeÿer, A
de Witte, T
机构：
[1] Univ Nijmegen Hosp, Dept Hematol 544, NL-6500 HB Nijmegen, Netherlands
[2] Univ Nijmegen Hosp, Dept Anthropogenet, NL-6500 HB Nijmegen, Netherlands
[3] Erasmus Univ, Dept Cell Biol & Genet, NL-3000 DR Rotterdam, Netherlands
来源：
ANNALS OF HEMATOLOGY | 1996年 / 72卷 / 06期
关键词：
busulfan; chronic myelogenous leukemia; cytogenetic; minimal residual disease; polymerase chain reaction;
D O I：
10.1007/s002770050188
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 44-year-old man suffering from cytogenetically and molecularly proven Philadelphia translocation-positive chronic myelogenous leukemia in chronic phase was treated with busulfan for 18 months and studied during a follow-up period of 13 years. Hematologically and cytogenetically, he attained a continuing complete remission, although at one point (9.5 years) at least, after attaining complete remission molecular analysis indicated the presence of minimal residual disease.
引用
收藏
页码：371 / 373
页数：3
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